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    Acamprosate, but not naltrexone, inhibits conditioned abstinence behaviour associated with repeated ethanol administration and exposure to a plus-maze

    Rationale: Drugs that reduce relapse in alcoholics are thought to inhibit either positive reinforcement for drinking (e.g. naltrexone) or negative reinforcement (e.g. acamprosate), and m...

    J. C. Cole, J. M. Littleton, H. J. Little in Psychopharmacology (2000)

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    Effects of repeated ethanol administration in the plus maze; a simple model for conditioned abstinence behaviour

    Classical conditioning is considered to be an important factor in drug dependence. Exposure to an environment in which alcohol has been repeatedly consumed may produce feelings of anxiety and dysphoria in a c...

    J. C. Cole, J. M. Littleton, H. J. Little in Psychopharmacology (1999)

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    Effects of dihydropyridine calcium channel antagonists in ethanol withdrawal; doses required, stereospecificity and actions of Bay K 8644

    The effects of dihydropyridine calcium channel antagonists, and the calcium channel activator, Bay K 8644, were examined on the convulsive behaviour induced by handling in mice following withdrawal from chroni...

    J. M. Littleton, H. J. Little, M. A. Whittington in Psychopharmacology (1990)