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Article
Dissection of CD20 regulation in lymphoma using RNAi
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Article
p53-dependent non-coding RNA networks in chronic lymphocytic leukemia
Mutations of the tumor suppressor p53 lead to chemotherapy resistance and a dismal prognosis in chronic lymphocytic leukemia (CLL). Whereas p53 targets are used to identify patient subgroups with impaired p53 ...
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Article
The impact of SF3B1 mutations in CLL on the DNA-damage response
Mutations or deletions in TP53 or ATM are well-known determinants of poor prognosis in chronic lymphocytic leukemia (CLL), but only account for approximately 40% of chemo-resistant patients. Genome-wide sequencin...