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Chapter
Molecular Genetics of Torpedo Marmorata Acetylcholine Receptor
The acetylcholine receptor (AcChoR) is one of the best known membrane-bound allosteric proteins (reviewed by Changeux, 1981; Changeux et al., 1984). Integrated in the post-synaptic membrane of the cholinergic syn...
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Chapter and Conference Paper
Tertiary Structure of the Nicotinic Acetylcholine Receptor Probed by Photolabeling and Protein Chemistry
The nicotinic Ach-receptor in vertebrates consists of four subunits assembled into an heterologous α2βγδ pentamer. The cDNAs coding for the constitutive four chains of the Ach-receptor have been cloned and sequen...
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Chapter
Allosteric Sites and Conformational Transitions of the Acetylcholine Receptor: Models for Short-term Regulation of Receptor Response
The word “receptor” is commonly used with two separate significations: for the site complementary to the structure of the chemical messenger and for the protein which carries the site. From a functional point of ...
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Chapter
Allosteric Sites and Conformational Transitions of the Acetylcholine Receptor: Models for Short-term Regulation of Receptor Response
The word “receptor” is commonly used with two separate significations: for the site complementary to the structure of the chemical messenger and for the protein which carries the site. From a functional point of ...
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Chapter
Topographical Analysis of the Torpedo Marmorata Acetylcholine Receptor by Energy Transfer Photoaffinity Labeling Using Aryldiazonium Derivatives
The acetylcholine and the non competitive blockers binding sites of the native, membrane-bound acetylcholine receptor from Torpedo Marmorata were covalently photo-labeled by aryldiazonium derivatives.These der...
