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Article
Associations of hemoglobin and change in hemoglobin with risk of incident hip fracture in older men and women: the cardiovascular health study
In a multi-site longitudinal cohort study, decreasing hemoglobin was associated with increased hip fracture risk in men. Anemia was associated with hip fracture in men and in African American women. Decreasing...
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Article
Biochemical markers of bone turnover and risk of incident hip fracture in older women: the Cardiovascular Health Study
The relationships of osteocalcin (OC) and C-telopeptide of type I collagen (CTX) with long-term incidence of hip fracture were examined in 1680 post-menopausal women from a population-based study. CTX, but not...
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Article
The associations of subclinical atherosclerotic cardiovascular disease with hip fracture risk and bone mineral density in elderly adults
In the absence of clinically recognized cardiovascular disease, increased carotid artery intimal medial thickness was associated with higher hip fracture risk in older adults, despite its association with high...
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Article
Association of DPP-4 activity with BMD, body composition, and incident hip fracture: the Cardiovascular Health Study
There was no association of plasma DPP-4 activity levels with bone mineral density (BMD), body composition, or incident hip fractures in a cohort of elderly community-dwelling adults.
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Article
Incident atrial fibrillation and the risk of fracture in the cardiovascular health study
In this prospective cohort of 4462 older adults, incident atrial fibrillation (AF) was not statistically significantly associated with subsequent risk of incident fracture.
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Article
Systemic markers of microvascular disease and bone mineral density in older adults
Here we report that abnormal brain white matter and, to a lesser extent, albuminuria are associated with reduced bone mineral density in the hip, spine, and total body in men and women. These findings may expl...
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Article
Soluble CD14 and fracture risk
Soluble CD14 (sCD14) is an inflammatory marker associated with osteoclasts. Using Cox proportional hazards models, we found a positive association between plasma levels of sCD14 and risk of incident fracture a...
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Article
Albuminuria is associated with hip fracture risk in older adults: the cardiovascular health study
The microcirculation plays an important role in bone health. Here, we examine whether albuminuria, a marker of renal microvascular disease, is associated with the risk of hip fracture in older adults (age, 78 ...
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Article
Renal function and nonvertebral fracture risk in multiethnic women: the Women’s Health Initiative (WHI)
To examine the association between renal function and fracture in multiethnic women, we studied postmenopausal women enrolled in the Women’s Health Initiative. Postmenopausal White women with mild renal dysfun...
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Article
Baseline serum estradiol and fracture reduction during treatment with hormone therapy: The Women's Health Initiative randomized trial
The purpose of the study was to test the hypothesis that the reduction in fractures with hormone therapy (HT) is greater in women with lower estradiol levels.
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Article
The emerging role of APC/CCdh1 in controlling differentiation, genomic stability and tumor suppression
Deregulation of the G1/G0 phase of the cell cycle can lead to cancer. During G1, most cells commit alternatively to DNA replication and division, or to cell-cycle exit and differentiation. The anaphase-promoti...
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Article
Alcohol consumption, bone density, and hip fracture among older adults: the cardiovascular health study
Previous studies have found inconsistent relationships of alcohol consumption with risk of hip fracture, and the importance of bone mineral density and risk of falls in mediating such a relationship has not be...
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Article
Risk factors for hip fracture in women with high BMD: EPIDOS study
Hip fractures are common among older women. At the present time, major efforts are being made to identify women with low bone mineral density (BMD). However, more than half of hip fractures occur in women who ...