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  1. No Access

    Article

    Studies on the clinical efficacy and pharmacokinetics of low-dose arsenic trioxide in the treatment of relapsed acute promyelocytic leukemia: a comparison with conventional dosage

    Twenty cases of patients with relapsed acute promyelocytic leukemia (APL) were entered into this study for evaluating the clinical efficacy and pharmacokinetics of low-dose arsenic trioxide (As2O3). As2O3 was giv...

    Y Shen, Z-X Shen, H Yan, J Chen, X-Y Zeng, J-M Li, X-S Li, W Wu, S-M **ong… in Leukemia (2001)

  2. No Access

    Article

    Clinical and cytogenetic features of 508 Chinese patients with myelodysplastic syndrome and comparison with those in Western countries

    Myelodysplastic syndrome (MDS) is a clonal hematopoietic stem cell disorder characterized by ineffective hematopoiesis and leukemia progression. Racial differences may exist on clinical pictures and the molecu...

    B Chen, W-L Zhao, J **, Y-Q Xue, X Cheng, X-T Chen, J Cui, Z-M Chen, Q Cao… in Leukemia (2005)

  3. No Access

    Article

    Molecular response in acute promyelocytic leukemia: a direct comparison of regular and real-time RT-PCR

    Evaluation of molecular response is important for the diagnosis and monitoring of minimal residual disease in patients with acute promyelocytic leukemia (APL). In this study, we analyzed the molecular response...

    Y-F Liu, Y-M Zhu, S-H Shen, Z-X Shen, J-M Li, S-J Chen, Z Chen, H U Jiong in Leukemia (2006)

  4. No Access

    Article

    MassARRAY assay: a more accurate method for JAK2V617F mutation detection in Chinese patients with myeloproliferative disorders

    J-F Fu, J-Y Shi, W-L Zhao, G Li, Q Pan, J-M Li, J Hu, Z-X Shen, J **, F-Y Chen… in Leukemia (2008)

  5. No Access

    Article

    AML1-ETO9a is correlated with C-KIT overexpression/mutations and indicates poor disease outcome in t(8;21) acute myeloid leukemia-M2

    AML1-ETO fusion gene is generated from chromosomal translocation t(8;21) mainly in acute myeloid leukemia M2 subtype (AML-M2). Its spliced variant transcript, AML1-ETO9a, rapidly induces leukemia in murine model....

    B Jiao, C-F Wu, Y Liang, H-M Chen, S-M **ong, B Chen, J-Y Shi, Y-Y Wang… in Leukemia (2009)

  6. No Access

    Article

    How to manage acute promyelocytic leukemia

    Acute promyelocytic leukemia (APL) is a unique subtype of acute myeloid leukemia (AML). The prognosis of APL is changing, from the worst among AML as it used to be, to currently the best. The application of all-t...

    J-Q Mi, J-M Li, Z-X Shen, S-J Chen, Z Chen in Leukemia (2012)

  7. No Access

    Article

    TGF-β1 suppression of microRNA-450b-5p expression: a novel mechanism for blocking myogenic differentiation of rhabdomyosarcoma

    Transforming growth factor beta 1 (TGF-β1) is the most potent inhibitor of myogenic differentiation (MyoD) of rhabdomyosarcoma (RMS); however, the underlying mechanisms of this inhibition remain unclear. In th...

    M M Sun, J F Li, L L Guo, H T **ao, L Dong, F Wang, F B Huang, D Cao, T Qin… in Oncogene (2014)

  8. No Access

    Article

    Cardiac autonomic neuropathy risk estimated by sudomotor function and arterial stiffness in Chinese subjects

    The SUDOSCAN test was recently developed to detect diabetic autonomic neuropathy early and screen for cardiac autonomic neuropathy (CAN) through assessment of sudomotor function. The aim of this study was to i...

    Q Zeng, S-Y Dong, M-L Wang, F Wang, J-M Li, X-L Zhao in Journal of Human Hypertension (2016)

  9. No Access

    Article

    Targeting HDAC3, a new partner protein of AKT in the reversal of chemoresistance in acute myeloid leukemia via DNA damage response

    Resistance to cytotoxic chemotherapy drugs remains as the major cause of treatment failure in acute myeloid leukemia. Histone deacetylases (HDAC) are important regulators to maintain chromatin structure and co...

    J Long, W Y Fang, L Chang, W H Gao, Y Shen, M Y Jia, Y X Zhang, Y Wang, H B Dou… in Leukemia (2017)