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  1. Article

    Erratum: FHIT loss confers cisplatin resistance in lung cancer via the AKT/NF-κB/Slug-mediated PUMA reduction

    Correction to: Oncogene (2015) 34, 2505−2515; doi:10.1038/onc.2014.184; published online 7 July 2014 Since the publication of the above article, the authors have noticed that the PUMA immunostainings in the ‘A...

    D-W Wu, M-C Lee, N-Y Hsu, T-C Wu, J-Y Wu, Y-C Wang, Y-W Cheng, C-Y Chen, H Lee in Oncogene (2017)

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  2. Article

    Open Access

    Integrative analyses of transcriptome sequencing identify novel functional lncRNAs in esophageal squamous cell carcinoma

    Long non-coding RNAs (lncRNAs) have a critical role in cancer initiation and progression, and thus may mediate oncogenic or tumor suppressing effects, as well as be a new class of cancer therapeutic targets. W...

    C-Q Li, G-W Huang, Z-Y Wu, Y-J Xu, X-C Li, Y-J Xue, Y Zhu, J-M Zhao, M Li… in Oncogenesis (2017)

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  3. No Access

    Article

    Noninvasive tracking of gene transcript and neuroprotection after gene therapy

    Gene therapy holds exceptional potential for translational medicine by improving the products of defective genes in diseases and/or providing necessary biologics from endogenous sources during recovery process...

    J Ren, Y I Chen, C H Liu, P-C Chen, H Prentice, J-Y Wu, P K Liu in Gene Therapy (2016)

  4. Article

    Erratum: FHIT loss confers cisplatin resistance in lung cancer via the AKT/NF-κB/Slug-mediated PUMA reduction

    Correction to: Oncogene (2015) 34, 2505–2515; doi:10.1038/onc.2014.184; published online 7 July 2014 Since the publication of the above paper, the authors found a misplacing band in Figure 2e. The correct vers...

    D-W Wu, M-C Lee, N-Y Hsu, T-C Wu, J-Y Wu, Y-C Wang, Y-W Cheng, C-Y Chen, H Lee in Oncogene (2015)

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  5. Article

    Erratum: FHIT loss confers cisplatin resistance in lung cancer via the AKT/NF-κB/Slug-mediated PUMA reduction

    Correction to: Oncogene (2015) 34, 2505–2515; doi:10.1038/onc.2014.184; published online 7 July 2014 Since the online publication of the above article, it has been noted that affiliation for M-C Lee was incorr...

    D-W Wu, M-C Lee, N-Y Hsu, T-C Wu, J-Y Wu, Y-C Wang, Y-W Cheng, C-Y Chen, H Lee in Oncogene (2015)

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  6. No Access

    Article

    FHIT loss confers cisplatin resistance in lung cancer via the AKT/NF-κB/Slug-mediated PUMA reduction

    Fragile histidine triad (FHIT) loss by the two-hit mechanism of loss of heterozygosity and promoter hypermethylation commonly occurrs in non-small cell lung cancer (NSCLC) and may confer cisplatin resistance i...

    D-W Wu, M-C Lee, N-Y Hsu, T-C Wu, J-Y Wu, Y-C Wang, Y-W Cheng, C-Y Chen, H Lee in Oncogene (2015)

  7. No Access

    Article

    The MZF1/c-MYC axis mediates lung adenocarcinoma progression caused by wild-type lkb1 loss

    Liver kinase B1 (LKB1) loss in lung adenocarcinoma is commonly caused by genetic mutations, but these mutations rarely occur in Asian patients. We recently reported wild-type LKB1 loss via the alteration of NK...

    L-H Tsai, J-Y Wu, Y-W Cheng, C-Y Chen, G-T Sheu, T-C Wu, H Lee in Oncogene (2015)

  8. No Access

    Article

    Phosphorylation of paxillin confers cisplatin resistance in non-small cell lung cancer via activating ERK-mediated Bcl-2 expression

    Paxillin (PXN) is required for receptor tyrosine kinase-mediated ERK activation, and the activation of the Raf/MEK/ERK cascade has been linked with Bcl-2 expression. We hypothesized that phosphorylation of PXN...

    D-W Wu, T-C Wu, J-Y Wu, Y-W Cheng, Y-C Chen, M-C Lee, C-Y Chen, H Lee in Oncogene (2014)

  9. No Access

    Article

    The neuronal repellent SLIT2 is a target for repression by EZH2 in prostate cancer

    The neuronal repellent SLIT2 is repressed in a number of cancer types primarily through promoter hypermethylation. SLIT2, however, has not been studied in prostate cancer. Through genome-wide location analysis...

    J Yu, Q Cao, J Yu, L Wu, A Dallol, J Li, G Chen, C Grasso, X Cao, R J Lonigro… in Oncogene (2010)

  10. No Access

    Article

    Indiscernible benefit of high-resolution HLA ty** in improving long-term clinical outcome of unrelated umbilical cord blood transplant

    The success of allogeneic hematopoietic stem cell transplantation depends in part on the accuracy of human leukocyte antigen (HLA) matching between the donor–recipient pair. The higher the number of matching H...

    C Liao, J Y Wu, Z P Xu, Y Li, X Yang, J S Chen, X W Tang… in Bone Marrow Transplantation (2007)

  11. No Access

    Chapter

    Alternative Pre-mRNA Splicing and Regulation of Programmed Cell Death

    Apoptosis or programmed cell death (PCD) is critical for development and homeostasis of multi-cellular organisms. It also plays an important role in pathogenesis of a large number of human diseases. PCD is und...

    J. Y. Wu, H. Tang, N. Havlioglu in Regulation of Alternative Splicing (2003)

  12. No Access

    Chapter

    Establishment of Callus Culture, Somatic Embryogenesis, and the Regeneration of Cotton Plants

    For the induction of genetic variability and genetic manipulation studies, it is essential that the cells in culture develop into complete plants. In cotton, callus capable of differentiation has been establis...

    J. Y. Wu, J. M. She, X. N. Cai, Y. P. S. Bajaj in Cotton (1998)

  13. No Access

    Article

    The differential release of amino acids and neuropeptides from purified subpopulations of mammalian GABAergic and cholinergic cerebrocortical synaptosomes

    GABAergic and cholinergic synaptosome populations were isolated by immunomagnetophoresis. Analysis of 8 amino acids showed that the GABAergic population was enriched in GABA (3 fold). The cholinergic populatio...

    P. D. Hughes, P. Foley, H. F. Bradford, M. Ghatei, N. Khandanian… in Neurochemical Research (1993)

  14. No Access

    Article

    Isolation and characterization of endogenous modulators for GABA system

    Pig brain extracts from both soluble and membrane fractions were found to contain potent inhibitors for GABA synthesizing enzyme, GAD, referred to as endogenous GAD inhibitors (EGIs) and for the binding of GAB...

    M. Yarom, J. Bao, X. -W. Tang, E. Wu, Y. H. Lee, W. H. Tsai… in Neurochemical Research (1992)

  15. No Access

    Article

    Localization of l-glutamate decarboxylase immunoreactivity in the major pelvic ganglion and in the coeliac-superior mesenteric ganglion complex of the rat

    The localization of l-glutamate decarboxylase (GAD), the GABA-synthesizing enzyme, was studied in the rat major pelvic ganglion and in the coeliac-superior mesenteric ganglion complex by indirect immunofluorescen...

    T. Karhula, O. Häppölä, T. Joh, J. -Y. Wu in Histochemistry (1988)

  16. No Access

    Article

    Optical monitoring of activity of many neurons in invertebrate ganglia during behaviors

    Optical methods for monitoring neuron activity were developed because these methods lend themselves to simultaneous multiple-site measurements. With the use of new voltage-sensitive dyes, the dye-related pharm...

    J. -Y. Wu, J. A. London, D. Zecevic, H. -P. Höpp, L. B. Cohen, Chun **ao in Experientia (1988)

  17. No Access

    Article

    GABA and GAD-like immunoreactivity in the primate retina

    GABA immunoreactivity was studied and compared with GAD immunoreactivity in the retinae of baboon, cynomolgus monkey and man. The central and peripheral parts of the retinae were investigated separately in cyn...

    E. Agardh, B. Ehinger, J. -Y. Wu in Histochemistry (1987)

  18. No Access

    Article

    Demonstration of enkephalin-, substance p- and glutamate decarboxylase-like immunoreactivity in cultured cells derived from newborn rat neostriatum

    The presence of cells exhibiting leucine-enkephalin-, substance P- and glutamate decarboxylase-like immunoreactivity was demonstrated in dissociated cultures from newborn rat neostriatum. The size and shape of...

    P. Panula, P. Emson, J. -Y. Wu in Histochemistry (1980)

  19. No Access

    Article

    Abnormalities of neurotransmitter enzymes in Huntington's chorea

    The activities ofl-glutamate decarboxylase (GAD), GABA-transaminase (GABA-T), choline acetyltransferase (CAT), and cysteic and cysteinesulfinic acids decarboxylase (CAD/CSAD) in putamen and frontal cortex in both...

    J. -Y. Wu, E. D. Bird, M. S. Chen, W. M. Huang in Neurochemical Research (1979)

  20. No Access

    Article

    Gamma-aminobutyric acid pathways in the cerebellum studied by retrograde and anterograde transport of glutamic acid decarboxylase antibody after in vivo injections

    Injections of characterized antibody against glutamic acid decarboxylase (GAD), the enzyme responsible for the synthesis of γ-aminobutyric acid (GABA), were made into the cerebellum. Small cortical injections ...

    Victoria Chan-Palay, Sanford L. Palay, J. -Y. Wu in Anatomy and Embryology (1979)