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Article
Open AccessCorrection: Cerebrospinal fluid tau levels are associated with abnormal neuronal plasticity markers in Alzheimer’s disease
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Article
Open AccessCerebrospinal fluid tau levels are associated with abnormal neuronal plasticity markers in Alzheimer’s disease
Increased total tau (t-tau) in cerebrospinal fluid (CSF) is a key characteristic of Alzheimer’s disease (AD) and is considered to result from neurodegeneration. T-tau levels, however, can be increased in very ...
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Article
Open AccessAPOE ε4 genotype-dependent cerebrospinal fluid proteomic signatures in Alzheimer’s disease
Aggregation of amyloid β into plaques in the brain is one of the earliest pathological events in Alzheimer’s disease (AD). The exact pathophysiology leading to dementia is still uncertain, but the apolipoprote...
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Article
Open AccessMRI predictors of amyloid pathology: results from the EMIF-AD Multimodal Biomarker Discovery study
With the shift of research focus towards the pre-dementia stage of Alzheimer’s disease (AD), there is an urgent need for reliable, non-invasive biomarkers to predict amyloid pathology. The aim of this study wa...
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Article
Open AccessThe EMIF-AD Multimodal Biomarker Discovery study: design, methods and cohort characteristics
There is an urgent need for novel, noninvasive biomarkers to diagnose Alzheimer’s disease (AD) in the predementia stages and to predict the rate of decline. Therefore, we set up the European Medical Informatio...
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Article
Open AccessCorrection to: Cerebrovascular and amyloid pathology in predementia stages: the relationship with neurodegeneration and cognitive decline
Upon publication of this article [1], it was noticed that there were some inconsistencies in Tables 1, 2 and 3. Some of the superscript letters were incorrectly assigned. Please see below the correct tables:
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Article
Open AccessCerebrovascular and amyloid pathology in predementia stages: the relationship with neurodegeneration and cognitive decline
Cerebrovascular disease (CVD) and amyloid-β (Aβ) often coexist, but their influence on neurodegeneration and cognition in predementia stages remains unclear. We investigated the association between CVD and Aβ ...