Skip to main content

3 Result(s)

within Imtiyaz Yaseen Remove this filter

and

  1. No Access

    Article

    Proteasome-dependent truncation of the negative heterochromatin regulator Epe1 mediates antifungal resistance

    Epe1 histone demethylase restricts H3K9-methylation-dependent heterochromatin, preventing it from spreading over, and silencing, gene-containing regions in fission yeast. External stress induces an adaptive re...

    Imtiyaz Yaseen, Sharon A. White… in Nature Structural & Molecular Biology (2022)

  2. No Access

    Article

    Epigenetic gene silencing by heterochromatin primes fungal resistance

    Heterochromatin that depends on histone H3 lysine 9 methylation (H3K9me) renders embedded genes transcriptionally silent1–3. In the fission yeast Schizosaccharomyces pombe, H3K9me heterochromatin can be transmitt...

    Sito Torres-Garcia, Imtiyaz Yaseen, Manu Shukla, Pauline N. C. B. Audergon… in Nature (2020)

  3. No Access

    Article

    Mycobacteria modulate host epigenetic machinery by Rv1988 methylation of a non-tail arginine of histone H3

    Mycobacteria are successful pathogens that modulate the host immune response through unclear mechanisms. Here we show that Rv1988, a secreted mycobacterial protein, is a functional methyltransferase that local...

    Imtiyaz Yaseen, Prabhjot Kaur, Vinay Kumar Nandicoori… in Nature Communications (2015)