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  1. No Access

    Article

    Epigenetic gene silencing by heterochromatin primes fungal resistance

    Heterochromatin that depends on histone H3 lysine 9 methylation (H3K9me) renders embedded genes transcriptionally silent1–3. In the fission yeast Schizosaccharomyces pombe, H3K9me heterochromatin can be transmitt...

    Sito Torres-Garcia, Imtiyaz Yaseen, Manu Shukla, Pauline N. C. B. Audergon… in Nature (2020)

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    Article

    Mycobacteria modulate host epigenetic machinery by Rv1988 methylation of a non-tail arginine of histone H3

    Mycobacteria are successful pathogens that modulate the host immune response through unclear mechanisms. Here we show that Rv1988, a secreted mycobacterial protein, is a functional methyltransferase that local...

    Imtiyaz Yaseen, Prabhjot Kaur, Vinay Kumar Nandicoori… in Nature Communications (2015)