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  1. No Access

    Article

    Interethnic differences in the relevance of CYP2C9 genotype and environmental factors for diclofenac metabolism in Hispanics from Cuba and Spain

    The aims of this study were to evaluate the diclofenac metabolism in Hispanics from Cuba and Spain and its relation to ethnicity, CYP2C9 genotypes and environmental factors. Diclofenac hydroxylation capacity (con...

    A Llerena, M Alvarez, P Dorado, I González, E Peñas-LLedó… in The Pharmacogenomics Journal (2014)

  2. No Access

    Article

    CYP2D6 genotype and debrisoquine hydroxylation phenotype in Cubans and Nicaraguans

    CYP2D6 genotype and debrisoquine metabolic ratio (MR) were analyzed in 133 Nicaraguan Mestizos (NMs) and 260 Cubans divided into Cuban Mestizos (CMs) and White Cubans (WCs). The frequencies of poor metabolizers (...

    A LLerena, P Dorado, R Ramírez, I González, M Álvarez… in The Pharmacogenomics Journal (2012)