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  1. Article

    ER stress (PERK/eIF2α phosphorylation) mediates the polyglutamine-induced LC3 conversion, an essential step for autophagy formation

    Expanded polyglutamine 72 repeat (polyQ72) aggregates induce endoplasmic reticulum (ER) stress-mediated cell death with caspase-12 activation and vesicular formation (autophagy). We examined this relationship ...

    Y Kouroku, E Fujita, I Tanida, T Ueno, A Isoai, H Kumagai… in Cell Death & Differentiation (2007)

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