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  1. Article

    Open Access

    Cinacalcet-mediated activation of the CaMKKβ-LKB1-AMPK pathway attenuates diabetic nephropathy in db/db mice by modulation of apoptosis and autophagy

    Apoptosis and autophagy are harmoniously regulated biological processes for maintaining tissue homeostasis. AMP-activated protein kinase (AMPK) functions as a metabolic sensor to coordinate cellular survival a...

    Ji Hee Lim, Hyung Wook Kim, Min Young Kim, Tae Woo Kim, Eun Nim Kim… in Cell Death & Disease (2018)

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  2. Article

    Open Access

    Calcimimetic restores diabetic peripheral neuropathy by ameliorating apoptosis and improving autophagy

    Decreased AMPK-eNOS bioavailability mediates the development of diabetic peripheral neuropathy (DPN) through increased apoptosis and decreased autophagy activity in relation to oxidative stress. Schwann cells ...

    You Chul Chung, Ji Hee Lim, Hyun Mi Oh, Hyung Wook Kim… in Cell Death & Disease (2018)

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  3. No Access

    Article

    Differentiation of astrocytes with characteristics of ventral midbrain from human embryonic stem cells

    Molecular and functional diversity among region-specific astrocytes is of great interest in basic neuroscience and the study of neurological diseases. In this study, we present the generation and characterizat...

    Gyu-Bum Yeon, Byeong-Min Jeon, Seo Hyun Yoo, Dongyun Kim… in Stem Cell Reviews and Reports (2023)