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1,795 Result(s)
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Discordant PD-L1 results between 28–8 and 22C3 assays are associated with outcomes of gastric cancer patients treated with nivolumab plus chemotherapy
We evaluated the concordance/discordance of PD-L1 staining results between the 28–8 and 22C3 assays and its impact on the efficacy outcomes of advanced gastric cancer patients treated with nivolumab plus chemo...
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Prognostic value of mismatch repair deficiency in patients receiving first-line fluoropyrimidine plus platinum for metastatic, recurrent, or unresectable gastric cancer
We examined the impact of mismatch repair (MMR) status on efficacy of first-line fluoropyrimidine plus platinum (FP) chemotherapy in patients with HER2-negative metastatic, recurrent, or unresectable gastric c...
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Factors associated with the efficacy of first-line nivolumab plus chemotherapy in advanced gastric cancer patients with deficient mismatch repair
We aimed to investigate clinicopathologic factors leading to different clinical outcomes in patients with deficient mismatch repair protein (d-MMR) gastric cancer (GC) treated with nivolumab plus chemotherapy ...
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Letter to the editor: 5-year follow-up results of a JCOG1104 (OPAS-1) phase III non-inferiority trial to compare 4 courses and 8 courses of S-1 adjuvant chemotherapy for pathological stage II gastric cancer
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Tennessee’s Burden: How Students Apply for State Financial Aid within One Southern State
Administrative burden, or the frictions individuals experience in accessing public programs, has implications for whether and which eligible individuals receive aid. While prior research documents barriers to ...
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Open AccessAssessment of traumatic mandibular nerve using MR neurography sequence: a preliminary study
Iatrogenic mandibular nerve damage resulting from oral surgeries and dental procedures is painful and a formidable challenge for patients and oral surgeons alike, mainly because the absence of objective and qu...
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Open Access2023 Korean Society of Echocardiography position paper for the diagnosis and management of valvular heart disease, part II: mitral and tricuspid valve disease
This manuscript represents the official position of the Korean Society of Echocardiography on valvular heart diseases. This position paper focuses on the diagnosis and management of valvular heart diseases wit...
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Open AccessVolume control strategy and patient survival in sepsis-associated acute kidney injury receiving continuous renal replacement therapy: a randomized controlled trial with secondary analysis
Optimal strategy for volume control and the clinical implication of achieved volume control are unknown in patients with sepsis-associated acute kidney injury (AKI) receiving continuous renal replacement thera...
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Open AccessEndogenous stem cell mobilization and localized immunosuppression synergistically ameliorate DSS-induced Colitis in mice
Stem cell therapy is a promising alternative for inflammatory diseases and tissue injury treatment. Exogenous delivery of mesenchymal stem cells is associated with instant blood-mediated inflammatory reactions...
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Open AccessArtificial intelligence-based radiographic extent analysis to predict tuberculosis treatment outcomes: a multicenter cohort study
Predicting outcomes in pulmonary tuberculosis is challenging despite effective treatments. This study aimed to identify factors influencing treatment success and culture conversion, focusing on artificial inte...
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Article
Coupled Problem Study with Structural Analysis Considering Barrier Filling of PMa-SynRM for Railway Vehicle
This paper investigates the structural-electromagnetic coupled problem of a permanent magnet assisted-synchronous reluctance motor (PMa-SynRM) for railway vehicles considering the barrier filling. The PMa-SynR...
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Meta-Model Based Blade Optimization Design Considering the Fluid Characteristics of Vehicle Energy Harvesting
The advancement of transportation machinery has played a crucial role in driving global economic and societal growth. However, this progress has also given rise to challenges, such as the depletion of chemical...
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Sambou Bamboo salt™ down-regulates the expression levels of angiotensin-converting enzyme 2 in activated human mast cells
Mast cells have a detrimental impact on coronavirus disease 2019 (COVID-19) caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection. Sambou Bamboo salt™ (BS) suppresses mast cell-media...
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Organ-specific response with first-line atezolizumab-bevacizumab versus lenvatinib for patients with advanced hepatocellular carcinoma
Immune checkpoint inhibitor (ICI)-based treatments have become the mainstay of first-line treatment for unresectable hepatocellular carcinoma (HCC), but there has been a concern that intrahepatic HCC lesions m...
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Sacubitril/valsartan and the risk of incident dementia in heart failure: a nationwide propensity-matched cohort study
Sacubitril acts to inhibit neprilysin and as neprilysin is involved in amyloid-beta degradation in the central nervous system, and there is concern that sacubitril/valsartan may increase the risk of dementia. ...
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Study on CO2 Emission Assessment of Heavy-Duty and Ultra-Heavy-Duty Vehicles Using Machine Learning
EU is actively moving towards the implementation of Euro-7 regulations, thus placing a strong emphasis on real-road emissions. Euro-7 introduced OBM (on-board monitoring), which is an enhancement of regulation...
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Open AccessThe ion channel TRPA1 is a modulator of the cocaine reward circuit in the nucleus accumbens
Drug addiction therapies commonly fail because continued drug use promotes the release of excessive and pleasurable dopamine levels. Because the connection between pleasure and drug use becomes hard-wired in t...
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SMARCA4-deficient undifferentiated gastric carcinoma: a case series and literature review
Undifferentiated gastric carcinoma, characterized by anaplastic cells lacking distinct features of cytological or architectural differentiation, poses diagnostic and therapeutic challenges. Recent studies have...
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Open AccessGlobal intracranial arterial tortuosity is associated with intracranial atherosclerotic burden
The effect of arterial tortuosity on intracranial atherosclerosis (ICAS) is not well understood. This study aimed to evaluate the effect of global intracranial arterial tortuosity on intracranial atherosclerot...
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Open AccessDifferential diagnosis of thyroid nodules using heterogeneity quantification software on ultrasound images: correlation with the Bethesda system and surgical pathology
Ultrasonography (US)-guided fine-needle aspiration cytology (FNAC) is the primary modality for evaluating thyroid nodules. However, in cases of atypia of undetermined significance (AUS) or follicular lesion of...