![Loading...](https://link.springer.com/static/c4a417b97a76cc2980e3c25e2271af3129e08bbe/images/pdf-preview/spacer.gif)
-
Article
Vaccine Development for Severe Fever with Thrombocytopenia Syndrome Virus in Dogs
Severe fever with thrombocytopenia syndrome (SFTS) is a life-threatening viral zoonosis. The causative agent of this disease is the Dabie bandavirus, which is usually known as the SFTS virus (SFTSV). Although the...
-
Article
Open AccessClinical course and risk factors for development and progression of interstitial lung disease in primary Sjögren’s syndrome
This single-center, retrospective study aimed to investigate the course and prognostic factors of patients with primary Sjögren syndrome-associated interstitial lung disease (pSS-ILD). We included 120 pSS pati...
-
Article
Characteristic alterations of gut microbiota in uncontrolled gout
Microbiome research has been on the rise recently for a more in-depth understanding of gout. Meanwhile, there is a need to understand the gut microbiome related to uric acid-lowering drug resistance. In this s...
-
Article
A prospective multi-centre study of susceptibility map-weighted MRI for the diagnosis of neurodegenerative parkinsonism
This study aimed to compare susceptibility map-weighted imaging (SMwI) using various MRI machines (three vendors) with N-3-fluoropropyl-2-β-carbomethoxy-3-β-(4-iodophe nyl)nortropane (18F-FP-CIT) PET in the diagn...
-
Article
Open AccessLipidome profile predictive of disease evolution and activity in rheumatoid arthritis
Lipid mediators are crucial for the pathogenesis of rheumatoid arthritis (RA); however, global analyses have not been undertaken to systematically define the lipidome underlying the dynamics of disease evoluti...
-
Article
Open AccessClinical significance of quantitative bone SPECT/CT in the evaluation of hand and wrist pain in patients with rheumatic disease
We investigated the diagnostic value of the maximum standardized uptake value (SUV) at hand and wrist joints for differentiating rheumatic diseases via bone single-photon emission computed tomography (SPECT)/c...
-
Article
Open AccessCacao powder supplementation attenuates oxidative stress, cholinergic impairment, and apoptosis in d-galactose-induced aging rat brain
Aging, a critical risk factor of several diseases, including neurodegenerative disorders, affects an ever-growing number of people. Cacao supplementation has been suggested to improve age-related neuronal defi...
-
Article
Self-care recommendations for patients with rheumatic diseases during the COVID-19 pandemic
-
Article
Open AccessDietary chokeberry and dried jujube fruit attenuates high-fat and high-fructose diet-induced dyslipidemia and insulin resistance via activation of the IRS-1/PI3K/Akt pathway in C57BL/6 J mice
The incidence of metabolic syndrome linked to dyslipidemia and insulin resistance has increased; thus, studies must be conducted to elucidate this phenomenon. The present study aimed to investigate the protect...
-
Article
The effect of extra-articular manifestations on tumor necrosis factor-α inhibitor treatment duration in patients with ankylosing spondylitis: nationwide data from the Korean College of Rheumatology BIOlogics (KOBIO) registry
Tumor necrosis factor-α inhibitor (TNFi) therapy has shown to be remarkably effective for treating ankylosing spondylitis (AS); however, nearly 30% of AS patients every year either stop TNFi therapy or switch ...
-
Article
Open AccessAssociation between brain-derived neurotrophic factor gene polymorphisms and fibromyalgia in a Korean population: a multicenter study
Several lines of evidence imply that brain-derived neurotrophic factor (BDNF) is involved in the pathophysiology of fibromyalgia (FM); in this regard, patients with FM have altered blood and cerebrospinal flui...
-
Article
Performance of the 2016 ACR-EULAR classification criteria for primary Sjogren’s syndrome in a Korean cohort
This study compared the performance of the newly proposed 2016 American College of Rheumatology (ACR)/European League Against Rheumatism (EULAR) criteria to the 2002 American–European Consensus Group (AECG) an...
-
Article
Open AccessInterleukin-1 receptor antagonist-mediated neuroprotection by umbilical cord-derived mesenchymal stromal cells following transplantation into a rodent stroke model
The human umbilical cord is a promising source of mesenchymal stromal cells (MSCs). Intravenous administration of human umbilical cord-derived MSCs (IV-hUMSCs) showed a favorable effect in a rodent stroke mode...
-
Article
Extracts of Chrysanthemum zawadskii attenuate oxidative damage to vascular endothelial cells caused by a highly reducing sugar
Endothelial cells are considered candidates for involvement in the pathogenesis of diabetic vascular complications, and prevention of endothelial cell damage may be important in pharmacological attempts to pre...
-
Article
Gelidibacter flavus sp. nov., Isolated from Activated Sludge of Seawater Treatment System
A Gram-stain-negative bacterial strain designated Con4T was isolated from activated sludge in a seawater treatment system. The strain was rod-shaped, motile, aerobic, and formed yellow-colored colonies on agar me...
-
Article
Grou** of various stains to develop programs for a front-loading washer
Stains from foodstuffs, cosmetics, and daily activities are frequently founded on our clothes. It is very annoying to remove stains, because extra treatment should be done before or after washing. A smart wash...
-
Article
Open AccessSevere ARDS caused by adenovirus: early initiation of ECMO plus continuous renal replacement therapy
The reported survival rates of patients with acute respiratory distress syndrome (ARDS) caused by human adenovirus (HAdV) pneumonia are poor. The results do not differ much in immunocompetent patients supporte...
-
Article
Open AccessHuman-to-mouse prion-like propagation of mutant huntingtin protein
Huntington’s disease (HD) is an autosomal dominant neurodegenerative disorder of the central nervous system (CNS) that is defined by a CAG expansion in exon 1 of the huntingtin gene leading to the production o...
-
Article
Correlating Parkinson’s disease motor symptoms with three-dimensional [18F]FP-CIT PET
To investigate the correlation between the striatal three-dimensional location and the Unified Parkinson’s Disease Rating Scale (UPDRS) motor score in the context of idiopathic Parkinson’s disease (PD) through...
-
Article
Paenibacillus alba nov., Isolated from Peat Soil
A white-colored bacterial strain designated J20-6T was isolated from peat soil collected in Russia. Based on the 16S rRNA gene sequence similarities, the strain J20-6T belonged to the genus Paenibacillus, and the...