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Article
Association of Cough Severity with Asthma Control and Quality of Life in Patients with Severe Asthma
Symptoms are important components in determining asthma control and in the adjustment of treatment levels. However, clinical relevance of cough in severe asthma is not well-understood. This study aimed to eval...
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Article
Open AccessPhenylacetic acid, an anti-vaginitis metabolite produced by the vaginal symbiotic bacterium Chryseobacterium gleum
The human microbiome contains genetic information that regulates metabolic processes in response to host health and disease. While acidic vaginal pH is maintained in normal conditions, the pH level increases i...
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Article
Open AccessOrthoID: profiling dynamic proteomes through time and space using mutually orthogonal chemical tools
Identifying proteins at organelle contact sites, such as mitochondria-associated endoplasmic reticulum membranes (MAM), is essential for understanding vital cellular processes, yet challenging due to their dyn...
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Article
Open AccessThe LKB1–TSSK1B axis controls YAP phosphorylation to regulate the Hippo–YAP pathway
The Hippo pathway’s main effector, Yes-associated protein (YAP), plays a crucial role in tumorigenesis as a transcriptional coactivator. YAP’s phosphorylation by core upstream components of the Hippo pathway, ...
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Article
Open AccessUnderstanding the molecular mechanism of pathogenic variants of BIR2 domain in XIAP-deficient inflammatory bowel disease
X-linked inhibitor of apoptosis protein (XIAP) deficiency causes refractory inflammatory bowel disease. The XIAP protein plays a pivotal role in the pro-inflammatory response through the nucleotide-binding oli...
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Chapter and Conference Paper
Machine Learning Algorithms for Process Optimization and Quality Prediction of Spinning in Textile Industries
In smart manufacturing, data-driven artificial in...
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Article
Open AccessEffects of fine particulate matter on bone marrow-conserved hematopoietic and mesenchymal stem cells: a systematic review
The harmful effects of fine particulate matter ≤2.5 µm in size (PM2.5) on human health have received considerable attention. However, while the impact of PM2.5 on the respiratory and cardiovascular systems has be...
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Article
Preliminary Investigation on Efficacy and Safety of Substance P-Coated Stent for Promoting Re-Endothelialization: A Porcine Coronary Artery Restenosis Model
Current polymer-based drug-eluting stents (DESs) have fundamental issues about inflammation and delayed re-endothelializaton of the vessel wall. Substance-P (SP), which plays an important role in inflammation ...
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Article
Active Debris Removal Simulations Using Spider-Web Space-Nets for KITSAT-1 Satellite
This paper conducts capture simulations using space-nets based on the spider-web structure for Korea’s first satellite, KITSAT-1 to investigate the capture performance of the spider-web space-net. A nonlinear ...
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Article
Open AccessStatistically unbiased prediction enables accurate denoising of voltage imaging data
Here we report SUPPORT (statistically unbiased prediction utilizing spatiotemporal information in imaging data), a self-supervised learning method for removing Poisson–Gaussian noise in voltage imaging data. S...
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Article
Open AccessInvestigating the electrical crosstalk effect between pixels in high-resolution organic light-emitting diode microdisplays
Organic light-emitting diode (OLED) microdisplays have received great attention owing to their excellent performance for augmented reality/virtual reality devices applications. However, high pixel density of O...
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Article
Open AccessLong-term efficacy of anti-IL-4 receptor antibody in a patient with aspirin-exacerbated respiratory disease and IgG4-related disease
Aspirin-exacerbated respiratory disease (AERD) and IgG4-related disease (IgG4RD) share a common pathway of Th2-mediated immune mechanism; there have been several cases of IgG4RD developed in patients with asth...
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Article
Optimized Electrospinnability and Chemical Crosslinking of Nanofiber Membranes with High-content Hyaluronic Acid for Anti-coagulant Application
Hyaluronic acid (HA)-based nanofibers have been widely used for various biomedical applications such as cosmetics, wound dressing, and tissue engineering scaffolds owing to their large active surface areas and...
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Article
Open AccessMorphological and morphometric study of the scapulae of Korean wild deer
Korean water deer (Hydropotes inermis argyropus; Heude, 1884) and Siberian roe deer (Capreolus pygargus; Pallas, 1771) are Korean wild deer classified in the tribe Capreolini. C. pygargus in Korea were previously...
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Article
Capture Simulation Using Space-Nets for Space Debris in Various Motions
In this study, capture simulation of space debris in various motions is conducted using a space-net. A nonlinear structural dynamics analysis code, ABAQUS, is used in the capture simulation. A general contact ...
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Article
Preclinical Evaluation of an Everolimus-Eluting Bioresorbable Vascular Scaffold Via a Long-Term Rabbit Iliac Artery Model
Biodegradable poly (l-lactic acid) (PLLA), a bio safe polymer with a large elastic modulus, is widely used in biodegradable medical devices. However, because of its poor mechanical properties, a PLLA strut mus...
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Article
Open AccessPrion infection modulates hematopoietic stem/progenitor cell fate through cell-autonomous and non-autonomous mechanisms
Studies of PrPC-derived prion disease generally focus on neurodegeneration. However, little is known regarding the modulation of hematopoietic stem progenitor cells (HSPCs) that express PrPC in prion infection. A...
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Article
Open AccessButyrate potentiates Enterococcus faecalis lipoteichoic acid-induced inflammasome activation via histone deacetylase inhibition
Enterococcus faecalis, a Gram-positive opportunistic pathogen having lipoteichoic acid (LTA) as a major virulence factor, is closely associated with refractory apical periodontitis. Short-chain fatty acids (SCFAs...
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Article
Open AccessCombined IgE neutralization and Bifidobacterium longum supplementation reduces the allergic response in models of food allergy
IgE is central to the development of allergic diseases, and its neutralization alleviates allergic symptoms. However, most of these antibodies are based on IgG1, which is associated with an increased risk of f...
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Article
Open AccessAuthor Correction: Human cardiac stem cells rejuvenated by modulating autophagy with MHY-1685 enhance the therapeutic potential for cardiac repair
