6 Result(s)
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Article
Open AccessThe LKB1–TSSK1B axis controls YAP phosphorylation to regulate the Hippo–YAP pathway
The Hippo pathway’s main effector, Yes-associated protein (YAP), plays a crucial role in tumorigenesis as a transcriptional coactivator. YAP’s phosphorylation by core upstream components of the Hippo pathway, ...
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Open AccessStatistically unbiased prediction enables accurate denoising of voltage imaging data
Here we report SUPPORT (statistically unbiased prediction utilizing spatiotemporal information in imaging data), a self-supervised learning method for removing Poisson–Gaussian noise in voltage imaging data. S...
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Article
Open AccessButyrate potentiates Enterococcus faecalis lipoteichoic acid-induced inflammasome activation via histone deacetylase inhibition
Enterococcus faecalis, a Gram-positive opportunistic pathogen having lipoteichoic acid (LTA) as a major virulence factor, is closely associated with refractory apical periodontitis. Short-chain fatty acids (SCFAs...
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Article
Open AccessHypothermic treatment reduces matrix metalloproteinase-9 expression and damage in the liver following asphyxial cardiac arrest in rats
Hypothermic treatment is known to protect organs against cardiac arrest (CA) and improves survival rate. However, few studies have evaluated the effects of hypothermia on CA-induced liver damages. This study w...
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Article
Open AccessIn vitro and in vivo inhibition of Helicobacter pylori by Lactobacilllus paracasei HP7
The efficacy of standard therapeutic strategies for Helicobacter pylori (H. pylori) infection is decreasing over time due to the emergence of drug-resistant strains. As an alternative, the present study investiga...
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Article
Open AccessAcute toxicity and cytotoxicity evaluation of Dendrobium moniliforme aqueous extract in vivo and in vitro
Dendrobium moniliforme (L.) Sw., an herb of the Orchidaceae family, has long been used in traditional medicine to strengthen bones, nourish the stomach, and promote the production of bodily fluid. Recently, polys...
