-
Article
Open AccessFormaldehyde exposure induces regulatory T cell-mediated immunosuppression via calcineurin-NFAT signalling pathway
In this study, we investigated the effects of Formaldehyde (FA) exposure on splenic immune responses wherein helper T cells become activated and differentiate into effector T and regulatory T cells. BALB/c mic...
-
Article
Open AccessNasal and Pulmonary Toxicity of Titanium Dioxide Nanoparticles in Rats
In recent decades, titanium dioxide (TiO2) nanoparticles have been used in various applications, including paints, coatings, and food. However, data are lacking on the toxicological aspects associated with their ...
-
Article
Open AccessStandardization of Bronchoalveolar Lavage Method Based on Suction Frequency Number and Lavage Fraction Number Using Rats
Bronchoalveolar lavage (BAL) is a useful tool in researches and in clinical medicine of lung diseases because the BAL fluid contains biochemical and cytological indicators of the cellular response to infection...
-
Article
Open AccessDose-response Effects of Bleomycin on Inflammation and Pulmonary Fibrosis in Mice
Many studies have reported that bleomycin, anti-cancer drug, induces pulmonary fibrosis as a side effect. However, few investigations have focused on the dose-response effects of bleomycin on pulmonary fibrosi...
