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  1. Article

    Open Access

    Vascular regeneration and skeletal muscle repair induced by long-term exposure to SDF-1α derived from engineered mesenchymal stem cells after hindlimb ischemia

    Despite recent progress in medical and endovascular therapy, the prognosis for patients with critical limb ischemia (CLI) remains poor. In response, various stem cells and growth factors have been assessed for...

    **-Ju Kim, Jae-Hyun Park, Hyeok Kim, Woo-Sup Sim in Experimental & Molecular Medicine (2023)

  2. Article

    Open Access

    Enhancement strategy for effective vascular regeneration following myocardial infarction through a dual stem cell approach

    Since an impaired coronary blood supply following myocardial infarction (MI) negatively affects heart function, therapeutic neovascularization is considered one of the major therapeutic strategies for cell-bas...

    Hyeok Kim, Soon-Jung Park, Jae-Hyun Park, Sunghun Lee in Experimental & Molecular Medicine (2022)

  3. Article

    Open Access

    Author Correction: Human cardiac stem cells rejuvenated by modulating autophagy with MHY-1685 enhance the therapeutic potential for cardiac repair

    Ji Hye Park, Hyeok Kim, Hyung Ryong Moon in Experimental & Molecular Medicine (2022)

  4. Article

    Open Access

    CU06-1004 enhances vascular integrity and improves cardiac remodeling by suppressing edema and inflammation in myocardial ischemia–reperfusion injury

    Ischemia–reperfusion (I/R) injury accelerates the cardiomyocytes (CMs) death by oxidative stress, and thereby deteriorates cardiac function. There has been a paradigm shift in the therapeutic perspective more ...

    Haiying Zhang, Hyeok Kim, Bong Woo Park, Minyoung Noh in Experimental & Molecular Medicine (2022)

  5. Article

    Open Access

    Human cardiac stem cells rejuvenated by modulating autophagy with MHY-1685 enhance the therapeutic potential for cardiac repair

    Stem cell-based therapies with clinical applications require millions of cells. Therefore, repeated subculture is essential for cellular expansion, which is often complicated by replicative senescence. Cellula...

    Ji Hye Park, Hyeok Kim, Hyung Ryong Moon in Experimental & Molecular Medicine (2021)