6 Result(s)
within
Hye-yun Jeong
Science, Humanities and Social Sciences, multidisciplinary
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Article
Open AccessLINCS L1000 dataset-based repositioning of CGP-60474 as a highly potent anti-endotoxemic agent
Sepsis is one of the most common clinical syndromes that causes death and disability. Although many studies have developed drugs for sepsis treatment, none have decreased the mortality rate. The aim of this st...
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Article
Open AccessBeneficial effect of statins in patients receiving chronic hemodialysis following percutaneous coronary intervention: A nationwide retrospective cohort study
The cardiovascular diseases are the leading cause of mortality in end-stage renal disease (ESRD) patients. However, roles of statins are still controversial in dialysis-dependent ESRD patients regardless of ha...
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Article
Open AccessChloroquine and amodiaquine enhance AMPK phosphorylation and improve mitochondrial fragmentation in diabetic tubulopathy
We investigated the effects of chloroquine (CQ) and amodiaquine (AQ) on AMPK phosphorylation in renal tubular cells in a diabetic environment in vivo and in vitro. We also examined whether CQ- or AQ-mediated AMPK...
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Article
Open AccessNatural product derivative BIO promotes recovery after myocardial infarction via unique modulation of the cardiac microenvironment
The cardiac microenvironment includes cardiomyocytes, fibroblasts and macrophages, which regulate remodeling after myocardial infarction (MI). Targeting this microenvironment is a novel therapeutic approach fo...
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Article
Open AccessMisorientation-angle-dependent electrical transport across molybdenum disulfide grain boundaries
Grain boundaries in monolayer transition metal dichalcogenides have unique atomic defect structures and band dispersion relations that depend on the inter-domain misorientation angle. Here, we explore misorien...
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Article
Open Access5-Azacytidine modulates interferon regulatory factor 1 in macrophages to exert a cardioprotective effect
Macrophages are actively involved in inflammatory responses during the progression of cardiac injury, including myocardial infarction (MI). A previous study showed that 5-azacytidine (5AZ), a DNA methylation i...
