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Article
Open AccessPINK1 deficiency impairs osteoblast differentiation through aberrant mitochondrial homeostasis
PTEN-induced kinase 1 (PINK1) is a serine/threonine-protein kinase in mitochondria that is critical for mitochondrial quality control. PINK1 triggers mitophagy, a selective autophagy of mitochondria, and is in...
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Article
Open AccessThe adipokine Retnla deficiency increases responsiveness to cardiac repair through adiponectin-rich bone marrow cells
Resistin-like alpha (Retnla) is a member of the resistin family and known to modulate fibrosis and inflammation. Here, we investigated the role of Retnla in the cardiac injury model. Myocardial infarction (MI)...
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Article
Open AccessRestoration of angiogenic capacity of diabetes-insulted mesenchymal stem cells by oxytocin
Angiogenesis is the main therapeutic mechanism of cell therapy for cardiovascular diseases, but diabetes is reported to reduce the function and number of progenitor cells. Therefore, we studied the effect of s...