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    ENC1 Modulates the Aggregation and Neurotoxicity of Mutant Huntingtin Through p62 Under ER Stress

    Huntington’s disease (HD) is a devastating neurodegenerative disorder, which is caused by the expression and aggregation of polyQ-expanded mutant huntingtin protein (mtHTT). While toxic mtHTT aggregates are pr...

    Huikyong Lee, Hye-Hyun Ahn, WonJae Lee, Yumin Oh, Hyunwoo Choi in Molecular Neurobiology (2016)