-
Article
Open AccessReduction of APOE accounts for neurobehavioral deficits in fetal alcohol spectrum disorders
A hallmark of fetal alcohol spectrum disorders (FASD) is neurobehavioral deficits that still do not have effective treatment. Here, we present that reduction of Apolipoprotein E (APOE) is critically involved i...
-
Article
Open AccessEvaluation of retrieval accuracy and visual similarity in content-based image retrieval of chest CT for obstructive lung disease
The aim of our study was to assess the performance of content-based image retrieval (CBIR) for similar chest computed tomography (CT) in obstructive lung disease. This retrospective study included patients wit...
-
Article
Cataract surgery with new monofocal intraocular lens enhanced for intermediate vision and standard monofocal intraocular lens for retinal disorder
To investigate the difference in the initial surgical results between a new monofocal intraocular lens (IOL) with enhanced intermediate vision and the standard monofocal IOL in patients with retinal disease.
-
Article
Polysaccharide-based natural polymer for an eco-friendly food packaging material
Polysaccharide, one of the most abundant polymers in nature, is utilized in diverse industrial fields, ranging from food to medicine, owing to its unique functional features and biological activity. The increa...
-
Article
Open AccessAdjuvant effects of combination monophosphoryl lipid A and poly I:C on antigen-specific immune responses and protective efficacy of influenza vaccines
Toll-like receptor (TLR) agonists improve vaccine immunogenicity and efficacy, but they are currently unlicensed as adjuvants in influenza vaccines. This study aimed to investigate whether a combination of mon...
-
Article
Open AccessFatty acid metabolism changes in association with neurobehavioral deficits in animal models of fetal alcohol spectrum disorders
Fetal alcohol spectrum disorders (FASD) show behavioral problems due to prenatal alcohol exposure (PAE). A previous study reports changes in gene expressions linked to fatty acid (FA) metabolism in the cerebra...
-
Article
Open AccessDNA double-strand break-free CRISPR interference delays Huntington’s disease progression in mice
Huntington’s disease (HD) is caused by a CAG repeat expansion in the huntingtin (HTT) gene. CRISPR-Cas9 nuclease causes double-strand breaks (DSBs) in the targeted DNA that induces toxicity, whereas CRISPR interf...
-
Article
Open AccessImage Turing test and its applications on synthetic chest radiographs by using the progressive growing generative adversarial network
The generative adversarial network (GAN) is a promising deep learning method for generating images. We evaluated the generation of highly realistic and high-resolution chest radiographs (CXRs) using progressiv...
-
Article
Open AccessMachine learning based potentiating impacts of 12-lead ECG for classifying paroxysmal versus non-paroxysmal atrial fibrillation
Conventional modality requires several days observation by Holter monitor to differentiate atrial fibrillation (AF) between Paroxysmal atrial fibrillation (PAF) and Non-paroxysmal atrial fibrillation (Non-PAF)...
-
Article
The risk of preterm birth in women with history of short cervix delivering at term in the previous pregnancy: a retrospective cohort study
To investigate whether women with a short cervical length (CL), but delivered at term in the first pregnancy might have increased risks of having short cervix and spontaneous preterm birth (sPTB) in the subseq...
-
Article
Histologic analysis according to HER2 gene status in HER2 2 + invasive breast cancer: a study of 280 cases comparing ASCO/CAP 2013 and 2018 guideline recommendations
The American Society of Clinical Oncology and College of American Pathologists guidelines for HER2 testing in breast cancer (BC) have been updated with more stringent criteria regarding immunohistochemistry (I...
-
Article
Open AccessActivation of the anterior cingulate cortex ameliorates anxiety in a preclinical model of fetal alcohol spectrum disorders
People with fetal alcohol spectrum disorders (FASD) are suffered from a wide range of interlinked cognitive and psychological problems. However, few therapeutic options are available for those patients due to ...
-
Chapter and Conference Paper
How Are the Issues of Poverty Changing with COVID-19 in South Korea?
This research attempts to extract major topics from the poverty-rela...
-
Chapter
Thoracic Imaging: Ventilation/Perfusion
Various lung diseases cause structural or reflex changes in the lungs, resulting in changes in ventilation or perfusion status, which lead to ventilation–perfusion imbalances. Various imaging methods, includin...
-
Article
Open AccessIdentification for antitumor effects of tramadol in a xenograft mouse model using orthotopic breast cancer cells
In our previous research showed that tramadol having potential anti-tumor effect was associated with enhancement of oncological prognosis in patients with breast cancer surgery. As these effects have not been ...
-
Article
Genetic changes in plaque-purified varicella vaccine strain Suduvax during in vitro propagation in cell culture
Infection by varicella-zoster virus (VZV) can be prevented by using live attenuated vaccines. VZV vaccine strains are known to evolve rapidly in vivo, however, their genetic and biological effects are not known. ...
-
Article
Open AccessPrognostic value of noggin protein expression in patients with resected gastric cancer
Noggin and RNA-binding protein for multiple splicing 2 (RBPMS2) are known to regulate the expression of smooth muscle cells, endothelial cells, and osteoblasts. However, the prognostic role of combined Noggin ...
-
Article
Recent glycemic control can predict the progressive motor deficits of acute subcortical infarction with diabetes or prediabetes
The predictors of progressive motor deficits in acute subcortical infarctions are still controversial. It is not known whether glycemic control influences on stroke progression.
-
Chapter
Functional Assessment of COPD
Chronic obstructive pulmonary disease (COPD) is a heterogeneous condition with variable clinical and pathophysiologic features. Functional information of the lungs is important to understand the complex pathop...
-
Article
Differentiation of predominant subtypes of lung adenocarcinoma using a quantitative radiomics approach on CT
To develop a model for differentiating the predominant subtype-based prognostic groups of lung adenocarcinoma using CT radiomic features, and to validate its performance in comparison with radiologists’ assess...
