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  1. Article

    Open Access

    Chronic olanzapine administration causes metabolic syndrome through inflammatory cytokines in rodent models of insulin resistance

    Olanzapine is a second-generation anti-psychotic drug used to prevent neuroinflammation in patients with schizophrenia. However, the long-term administration of olanzapine leads to insulin resistance (IR); the...

    Huqun Li, Shiyong Peng, Shihong Li, Shouqing Liu, Yifan Lv, Ni Yang… in Scientific Reports (2019)

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  2. No Access

    Article

    Pharmacokinetics and Tolerability of Rufinamide Following Single and Multiple Oral Doses and Effect of Food on Pharmacokinetics in Healthy Chinese Subjects

    Rufinamide is a triazole derivative that is structurally unrelated to currently marketed antiepileptic medications for add-on treatment of seizures in the setting of Lennox–Gastaut syndrome in patients from th...

    Mingzhen Xu, Yang Ni, Ying Zhou, **aomeng He… in European Journal of Drug Metabolism and Ph… (2016)

  3. No Access

    Article

    Pharmacokinetic Properties of Oral Lafutidine Tablets and the Effect of Food on its Pharmacokinetics in Healthy Chinese Subjects

    The aim of this study was to evaluate the pharmacokinetics (PK) of single and multiple doses of oral lafutidine tablets and the effect of food on the PK properties in healthy Chinese subjects. The tolerability...

    Shihong Li, Mingzhen Xu, Huqun Li, Juan Du, Weiyong Li in Advances in Therapy (2016)

  4. No Access

    Chapter and Conference Paper

    FE Research on Influence of Pouring Temperature on Thermal Fatigue Depth for Aluminum Alloy Die Casting Die

    A three-dimensional finite element model of the aluminum alloy front cover die casting die was established by PRO/E and PROCAST software. Thermal balance forming of die casting die and the influence of pouring...

    Chenggang Pan, Huqun Yang, Wenchao Ma… in Proceedings of the 5th International Confe… (2016)

  5. No Access

    Article

    Photocatalytic reduction of nitroarenes to azo compounds over N-doped TiO2: relationship between catalysts and chemical reactivity

    This work deals with selective reduction of aromatic nitro compounds to corresponding symmetrical substituted azo compounds using nitrogen-doped TiO2 nanoparticles as photocatalyst in the presence of a catalytic ...

    Huqun Wang, **aofeng Yang, Weifeng **ong… in Research on Chemical Intermediates (2015)

  6. Article

    Open Access

    Catalytic synthesis of 2-(N-benzyl-N-phenylamino) phenol by mesoporous Pd-doped TiO2: an environmentally benign approach

    A facile and environmentally route for catalytic Synthesis of 2-(N-benzyl-N-phenylamino) phenol under UV irradiation conditions has been developed in the presence of a catalytic amount of mesoporous Pd-doped TiO2

    Huqun Wang, Tiegang Hu, **aofeng Yang, Jun** Yan, Weifeng **ong… in Applied Nanoscience (2014)

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  7. Article

    Open Access

    A quantitatively-modeled homozygosity map** algorithm, qHomozygosityMap**, utilizing whole genome single nucleotide polymorphism genoty** data

    Homozygosity map** is a powerful procedure that is capable of detecting recessive disease-causing genes in a few patients from families with a history of inbreeding. We report here a homozygosity map** alg...

    Huqun*, Shun-ichiro Fukuyama, Hiroyuki Morino, Hiroshi Miyazawa… in BMC Bioinformatics (2010)

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  8. No Access

    Article

    Identification of IGFBP-6 as an effector of the tumor suppressor activity of SEMA3B

    SEMA3B, a member of class 3 semaphorins, is a tumor suppressor. Competition with vascular endothelial growth factor (VEGF)165 explains a portion of the activity, whereas the VEGF-independent mechanism was not elu...

    N Koyama, J Zhang, Huqun, H Miyazawa, T Tanaka, X Su, K Hagiwara in Oncogene (2008)