![Loading...](https://link.springer.com/static/c4a417b97a76cc2980e3c25e2271af3129e08bbe/images/pdf-preview/spacer.gif)
-
Article
Open AccessChronic olanzapine administration causes metabolic syndrome through inflammatory cytokines in rodent models of insulin resistance
Olanzapine is a second-generation anti-psychotic drug used to prevent neuroinflammation in patients with schizophrenia. However, the long-term administration of olanzapine leads to insulin resistance (IR); the...
-
Article
Pharmacokinetics and Tolerability of Rufinamide Following Single and Multiple Oral Doses and Effect of Food on Pharmacokinetics in Healthy Chinese Subjects
Rufinamide is a triazole derivative that is structurally unrelated to currently marketed antiepileptic medications for add-on treatment of seizures in the setting of Lennox–Gastaut syndrome in patients from th...
-
Article
Pharmacokinetic Properties of Oral Lafutidine Tablets and the Effect of Food on its Pharmacokinetics in Healthy Chinese Subjects
The aim of this study was to evaluate the pharmacokinetics (PK) of single and multiple doses of oral lafutidine tablets and the effect of food on the PK properties in healthy Chinese subjects. The tolerability...
-
Chapter and Conference Paper
FE Research on Influence of Pouring Temperature on Thermal Fatigue Depth for Aluminum Alloy Die Casting Die
A three-dimensional finite element model of the aluminum alloy front cover die casting die was established by PRO/E and PROCAST software. Thermal balance forming of die casting die and the influence of pouring...
-
Article
Photocatalytic reduction of nitroarenes to azo compounds over N-doped TiO2: relationship between catalysts and chemical reactivity
This work deals with selective reduction of aromatic nitro compounds to corresponding symmetrical substituted azo compounds using nitrogen-doped TiO2 nanoparticles as photocatalyst in the presence of a catalytic ...
-
Article
Open AccessCatalytic synthesis of 2-(N-benzyl-N-phenylamino) phenol by mesoporous Pd-doped TiO2: an environmentally benign approach
A facile and environmentally route for catalytic Synthesis of 2-(N-benzyl-N-phenylamino) phenol under UV irradiation conditions has been developed in the presence of a catalytic amount of mesoporous Pd-doped TiO2
-
Article
Open AccessA quantitatively-modeled homozygosity map** algorithm, qHomozygosityMap**, utilizing whole genome single nucleotide polymorphism genoty** data
Homozygosity map** is a powerful procedure that is capable of detecting recessive disease-causing genes in a few patients from families with a history of inbreeding. We report here a homozygosity map** alg...
-
Article
Identification of IGFBP-6 as an effector of the tumor suppressor activity of SEMA3B
SEMA3B, a member of class 3 semaphorins, is a tumor suppressor. Competition with vascular endothelial growth factor (VEGF)165 explains a portion of the activity, whereas the VEGF-independent mechanism was not elu...