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  1. Article

    Open Access

    Mechanistic insight into the functional transition of the enzyme guanylate kinase induced by a single mutation

    Dramatic functional changes of enzyme usually require scores of alterations in amino acid sequence. However, in the case of guanylate kinase (GK), the functional novelty is induced by a single (S→P) mutation, ...

    Yuebin Zhang, Huiyan Niu, Yan Li, Huiying Chu, Hujun Shen… in Scientific Reports (2015)

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