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  1. Article

    Open Access

    Tauopathy promotes spinal cord-dependent production of toxic amyloid-beta in transgenic monkeys

    Tauopathy, characterized by the hyperphosphorylation and accumulation of the microtubule-associated protein tau, and the accumulation of Aβ oligomers, constitute the major pathological hallmarks of Alzheimer’s...

    Zhuchi Tu, Sen Yan, Bofeng Han, Caijuan Li… in Signal Transduction and Targeted Therapy (2023)

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    Article

    PAM variants were associated with type 2 diabetes mellitus risk in the Chinese population

    This study aimed to assess the association between PAM single-nucleotide polymorphisms (SNPs) and T2DM risk in the Chinese population. We performed the genotype of PAM SNPs using Agena MassARRAY in 1002 subjects....

    Binwu Sheng, Huiyi Wei, Zhiying Li, Haoyang Wei… in Functional & Integrative Genomics (2022)