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  1. Article

    Open Access

    Deep learning approach for cancer subtype classification using high-dimensional gene expression data

    Studies have shown that classifying cancer subtypes can provide valuable information for a range of cancer research, from aetiology and tumour biology to prognosis and personalized treatment. Current methods u...

    Jiquan Shen, Jiawei Shi, Junwei Luo, Haixia Zhai, **aoyan Liu in BMC Bioinformatics (2022)

  2. Article

    Open Access

    BreakNet: detecting deletions using long reads and a deep learning approach

    Structural variations (SVs) occupy a prominent position in human genetic diversity, and deletions form an important type of SV that has been suggested to be associated with genetic diseases. Although various d...

    Junwei Luo, Hongyu Ding, Jiquan Shen, Haixia Zhai, Zhengjiang Wu in BMC Bioinformatics (2021)

  3. Article

    Open Access

    NEDD: a network embedding based method for predicting drug-disease associations

    Drug discovery is known for the large amount of money and time it consumes and the high risk it takes. Drug repositioning has, therefore, become a popular approach to save time and cost by finding novel indica...

    Renyi Zhou, Zhangli Lu, Huimin Luo, Ju **ang, Min Zeng, Min Li in BMC Bioinformatics (2020)

  4. Article

    Open Access

    Correction to: SLR: a scaffolding algorithm based on long reads and contig classification

    Following publication of the original article [1], the author reported that there is an error in the original article.

    Junwei Luo, Mengna Lyu, Ranran Chen, **aohong Zhang, Huimin Luo in BMC Bioinformatics (2020)

  5. Article

    Open Access

    SLR: a scaffolding algorithm based on long reads and contig classification

    Scaffolding is an important step in genome assembly that orders and orients the contigs produced by assemblers. However, repetitive regions in contigs usually prevent scaffolding from producing accurate result...

    Junwei Luo, Mengna Lyu, Ranran Chen, **aohong Zhang, Huimin Luo in BMC Bioinformatics (2019)