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  1. Article

    Open Access

    Understanding the relationship between circulating lipids and risk of chronic kidney disease: a prospective cohort study and large-scale genetic analyses

    This study aims to comprehensively investigate the phenotypic and genetic relationships between four common lipids (high-density lipoprotein cholesterol, HDL-C; low-density lipoprotein cholesterol, LDL-C; tota...

    Yutong Wang, Li Zhang, Wenqiang Zhang, Mingshuang Tang in Journal of Translational Medicine (2023)

  2. Article

    Open Access

    Impact of gallstone disease on the risk of stroke and coronary artery disease: evidence from prospective observational studies and genetic analyses

    Despite epidemiological evidence associating gallstone disease (GSD) with cardiovascular disease (CVD), a dilemma remains on the role of cholecystectomy in modifying the risk of CVD. We aimed to characterize t...

    Li Zhang, Wenqiang Zhang, Lin He, Huijie Cui, Yutong Wang, Xueyao Wu in BMC Medicine (2023)

  3. Article

    Open Access

    Temporal relationship between sleep duration and obesity among Chinese Han people and ethnic minorities

    No studies have assessed the association between sleep duration and obesity in Chinese ethnic minorities. Whether the relationship between sleep duration and obesity is different between Chinese Han people and...

    Zhengxing Xu, Min Chen, Yuntong Yao, Lisha Yu, Pei**g Yan, Huijie Cui in BMC Public Health (2023)

  4. Article

    Open Access

    Targeting fibrosis: mechanisms and clinical trials

    Fibrosis is characterized by the excessive extracellular matrix deposition due to dysregulated wound and connective tissue repair response. Multiple organs can develop fibrosis, including the liver, kidney, he...

    Manyu Zhao, Liqun Wang, Mengzhu Wang in Signal Transduction and Targeted Therapy (2022)