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Article

TGF-β1 accelerates the hepatitis B virus X-induced malignant transformation of hepatic progenitor cells by upregulating miR-199a-3p

Increasing evidence has suggested that liver cancer arises partially from transformed hepatic progenitor cells (HPCs). However, the detailed mechanisms underlying HPC transformation are poorly understood. In t...

Ke-shuai Dong, Yan Chen, Guang Yang, Zhi-bin Liao, Hong-wei Zhang… in Oncogene (2020)