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Open AccessJMJD5 inhibits lung cancer progression by facilitating EGFR proteasomal degradation
Aberrant activation of epidermal growth factor receptor (EGFR) signaling is closely related to the development of non-small cell lung cancer (NSCLC). However, targeted EGFR therapeutics such as tyrosine kinase...
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Article
Open AccessBeta-galactosidase gene family genome-wide identification and expression analysis of members related to fruit softening in melon (Cucumis melo L.)
Texture quality is impotent for melon (Cucumis melo L.) fruit. β-galactosidase (β-Gal, EC 3.2.1.23) is an important cell wall glycosyl hydrolase involved in fruit softening, However, the β-Gal gene (BGALs) family...
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Article
Emerging role of exosomal long non-coding RNAs in lung cancer
Lung cancer is one of the most common malignancies worldwide. Also, it is the leading cause of cancer morbidity and mortality in men. Despite advances in lung cancer diagnosis and treatment, novel approaches a...
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Article
Open AccessA MYBL2 complex for RRM2 transactivation and the synthetic effect of MYBL2 knockdown with WEE1 inhibition against colorectal cancer
Ribonucleotide reductase (RR) is a unique enzyme for the reduction of NDPs to dNDPs, the building blocks for DNA synthesis and thus essential for cell proliferation. Pan-cancer profiling studies showed that RR...
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Article
Open AccessDrought-induced ABA, H2O2 and JA positively regulate CmCAD genes and lignin synthesis in melon stems
Cinnamyl alcohol dehydrogenase (CAD) is an important enzyme functions at the last step in lignin monomer synthesis pathway. Our previous work found that drought induced the expressions of CmCAD genes and promoted...
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Article
Lignin synthesized by CmCAD2 and CmCAD3 in oriental melon (Cucumis melo L.) seedlings contributes to drought tolerance
CmCAD2 and CmCAD3 function more positively than CmCAD1 in oriental melon for lignin synthesis which is important to ensure internal water status and thus for drought tolerance.
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Article
Open AccessIsolation and functional validation of the CmLOX08 promoter associated with signalling molecule and abiotic stress responses in oriental melon, Cucumis melo var. makuwa Makino
Lipoxygenases (LOXs) play significant roles in abiotic stress responses, and identification of LOX gene promoter function can make an important contribution to elucidating resistance mechanisms. Here, we cloned t...
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Article
Open AccessiTRAQ-based Protein Profiling and Fruit Quality Changes at Different Development Stages of Oriental Melon
Oriental melon is one of the most popular crops for its nutritional and flavour quality. Components that determine melon quality, such as sugar, colour, texture, flavour and aroma, among other factors, accumul...
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Article
Exogenous spermidine enhances chilling tolerance of tomato (Solanum lycopersicum L.) seedlings via involvement in polyamines metabolism and physiological parameter levels
The aim of the study was to elucidate the effect of exogenous spermidine (Spd) on polyamines (PAs) metabolism and physiological parameter levels in the leaves of tomato under chilling stress. Chilling-sensitiv...
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Article
Polyamine metabolism and biosynthetic genes expression in tomato (Lycopersicon esculentum Mill.) seedlings during cold acclimation
To elucidate the possible involvement of polyamines (PAs) in the chilling tolerance of tomato, we have investigated the metabolism of PAs, physiological features including levels of compatible solutes (soluble...
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Article
Putrescine enhances chilling tolerance of tomato (Lycopersicon esculentum Mill.) through modulating antioxidant systems
Seedlings of two tomato (Lycopersicon esculentum Mill.) cultivars, cv. Mawa (chilling-resistant) and cv. Moneymaker (chilling-sensitive) were used to investigate the effects of exogenous putrescine (Put) on chill...
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Article
Biosorption of cadmium by a Cd2+-hyperresistant Bacillus cereus strain HQ-1 newly isolated from a lead and zinc mine
A Cd2+-hyperresistant bacterial strain HQ-1 was isolated from a lead–zinc mine. The strain was characterized and identified as Bacillus cereus based on morphology, physiological tests and 16S rRNA gene analysis. ...
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Article
Associated impact of inorganic fertilizers and pesticides on microbial communities in soils
This study was designed to examine the reaction of microbial communities to the associated impact of inorganic fertilizers and pesticides during laboratorial simulation for 90 days. Soils were sampled from fie...
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Article
Isolation of levoglucosan-assimilating microorganisms from soil and an investigation of their levoglucosan kinases
The phosphorylation activities of glucose and levoglucosan (1,6-anhydro-β-d-glucopyranose, LG) were studied in 26 types of LG-assimilating microorganisms isolated from four types of soil in China. The results sho...