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  1. No Access

    Article

    Advanced single-cell pooled CRISPR screening identifies C19orf53 required for cell proliferation based on mTORC1 regulators

    Multiplexed single-cell CRISPR screening has accelerated the systematic dissection of biological discoveries; however, the efficiency of CRISPR-based gene knockout has inherent limitations. Here, we present Do...

    Yulong Tang, Simeng Liao, Guang Liu, **a **ong, Hongnan Liu… in Cell Biology and Toxicology (2022)

  2. No Access

    Article

    Autophagy Dysfunction and mTOR Hyperactivation Is Involved in Surgery: Induced Behavioral Deficits in Aged C57BL/6J Mice

    Autophagy is crucial for cell survival, development, division, and homeostasis. The mammalian target of rapamycin (mTOR), which is the foremost negative controller of autophagy, plays a key role in many endoge...

    Yanhua Jiang, Yongjian Zhou, Hong Ma, Xuezhao Cao, Zhe Li… in Neurochemical Research (2020)

  3. No Access

    Article

    UPLC-QTOF/MS-Based Metabolomics Reveals the Protective Mechanism of Hydrogen on Mice with Ischemic Stroke

    As a reductive gas, hydrogen plays an antioxidant role by selectively scavenging oxygen free radicals. It has been reported that hydrogen has protective effects against nerve damage caused by ischemia–reperfus...

    Lilin Chen, Yufan Chao, Pengchao Cheng, Na Li, Hongnan Zheng… in Neurochemical Research (2019)

  4. No Access

    Article

    Structure and specificity of a permissive bacterial C-prenyltransferase

    Discovery and characterization of an unusually permissive C-prenyltransferase provides a biocatalytic route for generating novel prenylated compounds, including daptomycin derivatives with increased potency. ...

    Sherif I Elshahawi, Hongnan Cao, Khaled A Shaaban… in Nature Chemical Biology (2017)

  5. No Access

    Book

    Potato Staple Food Processing Technology

    Taihua Mu, Hongnan Sun… in SpringerBriefs in Food, Health, and Nutrition (2017)

  6. No Access

    Chapter

    Processing Technology of Potato Staple Foods

    To give readers and allied stakeholders a better understanding of how to produce potato staple food products for home cooking, pilot production, and industrial production, this chapter introduces the processin...

    Taihua Mu, Hongnan Sun, **ngli Liu in Potato Staple Food Processing Technology (2017)

  7. No Access

    Chapter

    Background and Introduction

    So readers can better understand why China has implemented a potato staple food strategy, and how to implement a potato staple food strategy, this chapter introduces potato planting and production, the current...

    Taihua Mu, Hongnan Sun, **ngli Liu in Potato Staple Food Processing Technology (2017)

  8. No Access

    Chapter

    Tailored Flour for Potato Staple Foods

    To give readers and allied stakeholders a better understanding of tailored flour for potato staple foods, this chapter introduces the processing technology of tailored flour for potato staple foods, a comparis...

    Taihua Mu, Hongnan Sun, **ngli Liu in Potato Staple Food Processing Technology (2017)

  9. No Access

    Chapter

    Types of Potato Staple Food: A Brief Description

    To give readers a more in-depth understanding of the categories and characteristics of potato staple food products, this chapter introduces traditional and modern potato staple foods, including steamed bread, ...

    Taihua Mu, Hongnan Sun, **ngli Liu in Potato Staple Food Processing Technology (2017)

  10. No Access

    Chapter

    Modern Trends and Innovation

    Nowadays, different concepts and developments were made that changed the global food market. Several innovations find their application in the processing of food products, for example, functional ingredients (...

    Taihua Mu, Hongnan Sun, **ngli Liu in Potato Staple Food Processing Technology (2017)

  11. No Access

    Chapter

    Factors Affecting the Quality of Potato Staple Foods

    Staple foods are important for the health of a population. Many factors can affect the quality of potato staple foods, including flour properties, water, mixing, fermentation condition, heating process, and ad...

    Taihua Mu, Hongnan Sun, **ngli Liu in Potato Staple Food Processing Technology (2017)

  12. No Access

    Chapter

    Improving the Nutritional Value of Potato Staple Foods

    In recent years, there has been a global trend towards the use of the natural substances present in the staple food as a source of functional ingredients. Staple foods have an important role in human nutrition...

    Taihua Mu, Hongnan Sun, **ngli Liu in Potato Staple Food Processing Technology (2017)

  13. No Access

    Article

    A review of the immunomodulatory role of dietary tryptophan in livestock and poultry

    Tryptophan, a nutritionally essential amino acid, is active in the regulation of immune responses in animals. The products of tryptophan metabolism, such as indoleamine 2,3-dioxygenase, kynurenine, quinolinic ...

    Miaomiao Bai, Hongnan Liu, Kang Xu, Abimbola Oladele Oso, **n Wu, Gang Liu… in Amino Acids (2017)

  14. No Access

    Article

    Key mediators of intracellular amino acids signaling to mTORC1 activation

    Mammalian target of rapamycin complex 1 (mTORC1) is activated by amino acids to promote cell growth via protein synthesis. Specifically, Ras-related guanosine triphosphatases (Rag GTPases) are activated by ami...

    Yehui Duan, Fengna Li, Kunrong Tan, Hongnan Liu, Yinghui Li, Yingying Liu… in Amino Acids (2015)