11 Result(s)
within
Hongli Chen
Nanotechnology
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Article
Enhanced population of excited single state strategy: irradiation and ultrasound dual-response and host tumor-driven nano-sensitizers construction in triple synergistic therapy
Phototheranostics is an emerging field in synergistic antitumor therapy in which irradiation and sensitizers are combined to produce reactive oxygen species (ROS), bio-images, and high temperatures. All of the...
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Article
Therapeutic sponge prevents postoperative breast cancer recurrence by sustainably dissociating into CD44-targeted nanoplatform
Locoregional recurrence and distant metastasis of breast cancer still pose a significant risk for patients’ survival. To address the clinical challenge, functional absorbable sponges (HA-SH/PP-Dox/Lap/COL I (H...
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Article
Colorimetric detection of alkaline phosphatase based on the off-on effect of light-responsive oxidase mimicking activity of covalent organic framework (Cu-TpBpy-COF) under near-neutral condition
A colorimetric strategy has been developed for the detection of alkaline phosphatase (ALP) activity based on the off-on effect of the catalytic activity of light-responsive oxidase mimics covalent organic fram...
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Article
Open AccessGene augmented nuclear-targeting sonodynamic therapy via Nrf2 pathway-based redox balance adjustment boosts peptide-based anti-PD-L1 therapy on colorectal cancer
Colorectal cancer is known to be resistant to immune checkpoint blockade (ICB) therapy. Sonodynamic therapy (SDT) has been reported to improve the efficacy of immunotherapy by inducing immunogenic cell death (...
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Article
In situ fabrication of 3D COF-300 in a capillary for separation of aromatic compounds by open-tubular capillary electrochromatography
Two-dimensional (2D) COFs have been successfully applied for various applications, such as capillary electrochromatography (CEC). Compared with 2D COFs, three-dimensional (3D) COFs have higher surface area and...
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Article
Yellow-emissive carbon dots as a fluorescent probe for chromium(VI)
The authors describe a one-step method for the preparation of yellow fluorescent carbon dots (CDs) starting from 4-aminoacetanilide hydrochloride and 4-acetamidobenzaldehyde. The CDs have excitation/emission p...
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Synthesis of orange-red emissive carbon dots for fluorometric enzymatic determination of glucose
The authors describe a method for the preparation of orange-red emissive carbon dots (CDs) with excitation/emission peaks at 520/582 nm. The CDs were hydrothermally prepared by a one-pot strategy from trimesic...
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Article
Smart Cu1.75S nanocapsules with high and stable photothermal efficiency for NIR photo-triggered drug release
Thermosensitive drug delivery systems (DDSs) face major challenges, such as remote and repeatable control of in vivo temperature, although these can increase the therapeutic efficacy of drugs. To address this iss...
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Article
Development of NIR-II fluorescence image-guided and pH-responsive nanocapsules for cocktail drug delivery
Nanocapsule-based targeted delivery and stimulus-responsive release can increase drug effectiveness, while reducing the side effects of the drug. However, difficulties in the scale-up synthesis, fast burst rel...
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Article
One-pot, large-scale synthesis silica-encapsulated NIR alloy quantum dots CdSeTe within short time
Silica-based near-infrared fluorescent materials in biological application have attracted much attention. But the current methods for preparing silica-encapsulated near-infrared radiation (NIR) quantum dots (Q...
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Article
Open AccessA Novel Docetaxel-Loaded Poly (ε-Caprolactone)/Pluronic F68 Nanoparticle Overcoming Multidrug Resistance for Breast Cancer Treatment
Multidrug resistance (MDR) in tumor cells is a significant obstacle to the success of chemotherapy in many cancers. The purpose of this research is to test the possibility of docetaxel-loaded poly (ε-caprolact...
