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  1. Article

    Open Access

    UBN2 promotes tumor progression via the Ras/MAPK pathway and predicts poor prognosis in colorectal cancer

    Ubinuclein-2 (UBN2) is a nuclear protein that interacts with many transcription factors. The molecular role and mechanism of UBN2 in the development and progression of cancers, including colorectal cancer (CRC...

    Ya-li Zhao, Shen-Rong Zhong, Shi-Hong Zhang, Jia-**n Bi in Cancer Cell International (2019)

  2. Article

    Open Access

    Hypermethylation of DMTN promotes the metastasis of colorectal cancer cells by regulating the actin cytoskeleton through Rac1 signaling activation

    Colorectal cancer (CRC) is one of the most common digestive malignant tumors, and DMTN is a transcriptionally differentially expressed gene that was identified using CRC mRNA sequencing data from The Cancer Ge...

    Ya-** Ye, Hong-Li Jiao, Shu-Yang Wang in Journal of Experimental & Clinical Cancer … (2018)

  3. Article

    Open Access

    miR-422a inhibits cell proliferation in colorectal cancer by targeting AKT1 and MAPK1

    miRNAs are regarded as molecular biomarkers and therapeutic targets for colorectal cancer (CRC), a series of miRNAs have been proven to involve into CRC carcinogenesis, invasion and metastasis. Aberrant miR-42...

    Wen-Ting Wei, **n-**n Nian, Shu-Yang Wang, Hong-Li Jiao in Cancer Cell International (2017)