5 Result(s)
within
Holly Matthews
Biomedicine
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Article
Open AccessBulk‐up synchronization of successive larval cohorts of Anopheles gambiae and Anopheles coluzzii through temperature reduction at early larval stages: effect on emergence rate, body size and mating success
Malaria persists as a huge medical and economic burden. Although the number of cases and death rates have reduced in recent years, novel interventions are a necessity if such gains are to be maintained. Altern...
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Article
Open AccessChecks and balances? DNA replication and the cell cycle in Plasmodium
It is over 100 years since the life-cycle of the malaria parasite Plasmodium was discovered, yet its intricacies remain incompletely understood - a knowledge gap that may prove crucial for our efforts to control ...
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Open AccessDrug repositioning as a route to anti-malarial drug discovery: preliminary investigation of the in vitro anti-malarial efficacy of emetine dihydrochloride hydrate
Drug repurposing or repositioning refers to the usage of existing drugs in diseases other than those it was originally used for. For diseases like malaria, where there is an urgent need for active drug candida...
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Open AccessVariation in apoptosis mechanisms employed by malaria parasites: the roles of inducers, dose dependence and parasite stages
Plasmodium berghei ookinetes exhibit an apoptotic phenotype when develo** within the mosquito midgut lumen or when cultured in vitro. Markers of apoptosis increase when they are exposed to nitric oxide or react...
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Article
Antibody Responses of Healthy Infants to Concurrent Administration of a Bivalent Haemophilus influenzae Type b-Hepatitis B Vaccine with Diphtheria-Tetanus-Pertussis, Polio and Measles-Mumps-Rubella Vaccines
Objective: To confirm that children given a bivalent Haemophilus influenzae type b-hepatitis B vaccine (bivalent Hib-HB vaccine; COMVAX™) concurrently with priming doses of diphtheria-tetanus-per...
