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Absorption, distribution, metabolism, and excretion of CKD-732, a novel antiangiogenic fumagillin derivative, in rats, mice, and dogs
The pharmacokinetics of CKD-732 (6-0-4-[dimethyl-aminoethoxy)cinnamoyl]-fumagillol hemioxalate) was investigated in male SD rats and beagle dogs after bolus intravenous administration. The parent compound and ...