101 Result(s)
within
Ho ** Kim
Science, Humanities and Social Sciences, multidisciplinary
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Article
Open AccessTunable translation-level CRISPR interference by dCas13 and engineered gRNA in bacteria
Although CRISPR-dCas13, the RNA-guided RNA-binding protein, was recently exploited as a translation-level gene expression modulator, it has still been difficult to precisely control the level due to the lack o...
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Open AccessUsing isometric log-ratio in compositional data analysis for develo** a groundwater pollution index
This study introduces a novel groundwater pollution index (GPI) formulated through compositional data analysis (CoDa) and robust principal component analysis (RPCA) to enhance groundwater quality assessment. U...
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Open AccessFunctional characterization of plant specific Indeterminate Domain (IDD) transcription factors in tomato (Solanum lycopersicum L.)
Plant-specific transcription factors (TFs) are responsible for regulating the genes involved in the development of plant-specific organs and response systems for adaptation to terrestrial environments. This in...
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Open AccessTranspedicular injection of rhBMP-2 with β-tricalcium phosphate to reduce the proximal junctional kyphosis after adult spinal deformity correction: preliminary study
The aim of this preliminary study was to assess the impact of injecting recombinant human bone morphogenetic protein-2 (rhBMP-2) with β-tricalcium phosphate (β-TCP) carrier into the uppermost instrumented vert...
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Open AccessShort-term neonatal and long-term neurodevelopmental outcome of children born term low birth weight
This study aimed to examine the impact of term LBW on short-term neonatal and long-term neurodevelopmental outcomes in children 5–7 years of age. This is a population-based cohort study that merged national da...
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Open Access3D microprinting of inorganic porous materials by chemical linking-induced solidification of nanocrystals
Three-dimensional (3D) microprinting is considered a next-generation manufacturing process for the production of microscale components; however, the narrow range of suitable materials, which include mainly pol...
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Open AccessClinical manifestations and associated factors of uveitis in patients with pulmonary sarcoidosis: a case control study
Sarcoidosis, an idiopathic and inflammatory disease, affects various organs and can manifest as uveitis. Due to limited evidence, researchers investigated the risk factors associated with uveitis in patients w...
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Open AccessInhibitory effect of Sanguisorba hakusanensis Makino ethanol extract on atopic dermatitis-like responses in NC/Nga mice and human keratinocytes
Atopic dermatitis (AD) is an allergic, inflammatory skin disease caused by immune dysregulation. In this study, we investigated anti-atopic and anti-inflammatory activities of Sanguisorba hakusanensis ethanol ext...
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Open AccessLifestyle practices that reduce seasonal PM2.5 exposure and their impact on COPD
Particulate matter (PM) is a major air pollutant that has led to global health concerns and can cause and exacerbate chronic obstructive pulmonary disease (COPD). We asked patients with COPD to complete a deta...
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Open AccessInsulin-like growth factor binding protein-3 induces senescence by inhibiting telomerase activity in MCF-7 breast cancer cells
Insulin-like growth factor binding protein-3 (IGFBP-3) has been known to inhibit cell proliferation and exert tumor-suppressing effects depending on the cell type. In this study, we aimed to show that IGFBP-3 ...
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Open AccessUnderweight and risk of fractures in adults over 40 years using the nationwide claims database
We aimed to investigate how underweight affects the incidence of fractures, as well as the influence of cumulative, longitudinal periods of low body mass index (BMI) and changes in body weight on fracture deve...
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Open AccessPrediction of respiratory complications by quantifying lung contusion volume using chest computed tomography in patients with chest trauma
Pulmonary contusion is an important risk factor for respiratory complications in trauma patients. Hence, we aimed to determine the relationship between the ratio of pulmonary contusion volume to the total lung...
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Open AccessClinical impact of weight loss on mortality in patients with idiopathic pulmonary fibrosis: a retrospective cohort study
Patients with idiopathic pulmonary fibrosis (IPF) often experience weight loss during the follow-up period. However, the prevalence and clinical impact of weight loss in these patients still need to be elucida...
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Open AccessSingle-molecule fingerprinting of protein-drug interaction using a funneled biological nanopore
In drug discovery, efficient screening of protein-drug interactions (PDIs) is hampered by the limitations of current biophysical approaches. Here, we develop a biological nanopore sensor for single-molecule de...
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Open AccessAuthor Correction: Federated learning enables big data for rare cancer boundary detection
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Open AccessImpact of thyroid cancer on the cancer risk in patients with non-alcoholic fatty liver disease or dyslipidemia
The raised prevalence of obesity has increased the incidence of obesity-related metabolic diseases such as dyslipidemia (DL) and non-alcoholic fatty liver disease (NAFLD), along with the development and progre...
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Open AccessIncidence, risk factors, and clinical characteristics of airway complications after lung transplantation
Airway complications may occur after lung transplantation and are associated with considerable morbidity and mortality. We investigated the incidence, risk factors, and clinical characteristics of these compli...
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Open AccessBlast resistance of RC tubular structure under internal ANFO explosion
The degree of structural damage is significantly more severe when a blast occurs inside than outside of a structure. However, existing designs for RC structures such as reinforced concrete containment vessels ...
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Open AccessFederated learning enables big data for rare cancer boundary detection
Although machine learning (ML) has shown promise across disciplines, out-of-sample generalizability is concerning. This is currently addressed by sharing multi-site data, but such centralization is challenging...
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Open AccessPD-L1-directed PlGF/VEGF blockade synergizes with chemotherapy by targeting CD141+ cancer-associated fibroblasts in pancreatic cancer
Pancreatic ductal adenocarcinoma (PDAC) has a poor 5-year overall survival rate. Patients with PDAC display limited benefits after undergoing chemotherapy or immunotherapy modalities. Herein, we reveal that ch...
