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  1. Article

    Open Access

    JNETS clinical practice guidelines for gastroenteropancreatic neuroendocrine neoplasms: diagnosis, treatment, and follow-up: a synopsis

    Neuroendocrine neoplasms (NENs) are rare neoplasms that occur in various organs and present with diverse clinical manifestations. Pathological classification is important in the diagnosis of NENs. Treatment st...

    Tetsuhide Ito, Toshihiko Masui, Izumi Komoto, Ryuichiro Doi in Journal of Gastroenterology (2021)

  2. No Access

    Article

    Collision of a pancreatic ductal adenocarcinoma and a pancreatic neuroendocrine tumor associated with multiple endocrine neoplasm type 1

    A 54-year-old man with pancreatic head tumor had undergone pancreaticoduodenectomy and was diagnosed with pancreatic neuroendocrine tumor (P-NET) associated with sporadic multiple endocrine neoplasm type 1. Fi...

    Akihisa Ohno, Nao Fujimori, Masami Miki in Clinical Journal of Gastroenterology (2021)

  3. Article

    Advances in the diagnosis and treatment of pancreatic neuroendocrine neoplasms in Japan

    Several new developments have occurred in the field of pancreatic neuroendocrine neoplasm (PNEN) recently in Japan. First, the utility of chromogranin A (CgA), useful for the diagnosis and monitoring of the tr...

    Tetsuhide Ito, Susumu Hijioka, Toshihiko Masui in Journal of Gastroenterology (2017)

  4. Article

    Evidence-based clinical practice guidelines for chronic pancreatitis 2015

    Chronic pancreatitis is considered to be an irreversible progressive chronic inflammatory disease. The etiology and pathology of chronic pancreatitis are complex; therefore, it is important to correctly unders...

    Tetsuhide Ito, Hiroshi Ishiguro, Hirotaka Ohara in Journal of Gastroenterology (2016)

  5. Article

    Epidemiological trends of pancreatic and gastrointestinal neuroendocrine tumors in Japan: a nationwide survey analysis

    Although neuroendocrine tumors (NETs) are rare, the number of patients with NET is increasing. However, in Japan, there have been no epidemiological studies on NET since 2005; thus, the prevalence of NET rema...

    Tetsuhide Ito, Hisato Igarashi, Kazuhiko Nakamura in Journal of Gastroenterology (2015)

  6. No Access

    Article

    Pancreatic involvement in Japanese patients with von Hippel-Lindau disease: results of a nationwide survey

    The frequency and prognosis of pancreatic endocrine tumors (PNET)/pancreatic cystic tumors (PCT) in Japanese patients with von Hippel-Lindau disease (VHL) are still open to question.

    Hisato Igarashi, Tetsuhide Ito, Isao Nishimori, Kenji Tamura in Journal of Gastroenterology (2014)

  7. No Access

    Article

    Therapy of metastatic pancreatic neuroendocrine tumors (pNETs): recent insights and advances

    Neuroendocrine tumors (NETs) [carcinoids, pancreatic neuroendocrine tumors (pNETs)] are becoming an increasing clinical problem because not only are they increasing in frequency, but they can frequently presen...

    Tetsuhide Ito, Hisato Igarashi, Robert T. Jensen in Journal of Gastroenterology (2012)

  8. No Access

    Article

    Regulatory T cells expanded by rapamycin in vitro suppress colitis in an experimental mouse model

    To provide rapid immunosuppression without side effects, we analyzed whether rapamycin alone, and regulatory T cells (Tregs) expanded ex vivo by rapamycin, suppressed colitis in a mouse model.

    Haruei Ogino, Kazuhiko Nakamura, Tsutomu Iwasa, Eikich Ihara in Journal of Gastroenterology (2012)

  9. No Access

    Article

    Epidemiological study of gastroenteropancreatic neuroendocrine tumors in Japan

    There have been few epidemiological studies on gastroenteropancreatic neuroendocrine tumors (GEP-NETs) in Japan.

    Tetsuhide Ito, Hironobu Sasano, Masao Tanaka in Journal of Gastroenterology (2010)

  10. No Access

    Article

    The current managements of pancreatic diabetes in Japan

    Pancreatic diabetes is secondary diabetes followed by progressions of pancreatic exocrine diseases, such as chronic pancreatitis, pancreatic neoplasm and post-pancreatectomy. Because of destruction and reducti...

    Ken Kawabe, Tetsuhide Ito, Hisato Igarashi in Clinical Journal of Gastroenterology (2009)

  11. No Access

    Article

    Primary pancreatic low-grade mucosa-associated lymphoid tissue lymphoma presenting with multiple masses

    The case concerns a 55-year-old Japanese man with multiple pancreatic tumors that were incidentally detected by ultrasonography (US) in a routine medical examination. He consulted a doctor since either neuroen...

    Taichi Nakamura, Tetsuhide Ito, Yasunobu Abe in Clinical Journal of Gastroenterology (2008)

  12. No Access

    Article

    The time course of gap-junctional protein connexin 32 expression in the pancreas after the induction of acute pancreatitis by caerulein in rats

    We previously demonstrated that the immunostaining of the gap-junction protein, connexin 32 (Cx 32), in the pancreas was markedly reduced in caerulein (Cn)-induced acute pancreatitis. The expression of Cx 32 ...

    Keiichiro Ogoshi, Tetsuhide Ito, Hisato Igarashi in Journal of Gastroenterology (2002)