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Article
Ventricular Repolarization Dispersion is a Potential Risk for the Development of Life-Threatening Arrhythmia in Children with Hypertrophic Cardiomyopathy
The risk stratification and early interventions are necessary in patients with hypertrophic cardiomyopathy (HCM), as life-threatening arrhythmia (LTA) is a leading cause of death. This study aimed to explore w...
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Article
Germinoma in cerebral hemisphere associated with Down syndrome
A Down syndrome patient with germinoma develo** in the cerebral hemisphere is reported. A review of the literature yielded only 14 cases of Down syndrome with brain tumors, including our case. This finding ...
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Article
Effectiveness of intraoperative radiation therapy for recurrent supratentorial low grade glioma
Twelve adult patients in the records of 38 patients with histologically verified supratentorial low grade glioma showed recurrence at the Gifu University Hospital between 1980 and 1992. A mean period to recurr...
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Article
Long-term survival in malignant intracranial germ-cell tumors: a report of two cases and a review of the literature
The authors report the successful treatment of two cases of malignant germ-cell tumor. A 12-year-old patient with a pineal immature teratoma and increase of α-fetoprotein serum levels was treated with total ex...
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Article
Identification of placental form of glutathione s-transferase in ACNU-resistant murine glioma cell lines
Expression of the placental form of glutathione S-transferase (GST-P) in 1-(4-amino-2-methyl-5-pyrimidinyl) methyl-3-(2-chloro-ethyl)-3-nitrosourea hydrochloride (ACNU)-sensitive 9L and C6 glioma cells, and AC...
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Article
Immunoblot analysis of the placental form of glutathione S-transferase in protein extracted from paraffin-embedded human glioma tissue
Protein extracted from conventional formalin-fixed and paraffin-embedded tissue sections of human gliomas was examined for immunoblot analysis using antibody against the placental form of glutathioneS-transferase...
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Article
Histochemistry with Helix pomatia agglutinin in human germ cell tumors: detection of nongerminomatous components and correlation between HPA reactivity and radiosensitivity in germinomas
Binding sites of Helix pomatia agglutinin (HPA) were examined in 32 patients with intracranial human germ cell tumors. HPA reactivity was found in vascular endothelial cells and erythrocytes of patients with bloo...
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Article
Expression of the placental form of glutathione S-transferase in pediatric gliomas
Expression of the human placental form of glutathione S-transferase (GST-θ) in pediatric gliomas, consisting of three pilocytic astrocytomas (grade 1), two fibrillary astrocytomas (grade 2), three anaplastic a...
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Article
Sensitization of C6 glioma cells to radiation by staurosporine, a potent protein kinase C inhibitor
The effect of staurosporine, a potent protein kinase C (PKC) inhibitor, on the sensitivity to radiation has been investigated in C6 glioma cells. Pretreatment of C6 cells with staurosporine at the concentratio...
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Article
Proliferative assessment of craniopharyngioma and epidermoid by nucleolar organizer region staining
The histologic distinction between craniopharyngioma and epidermoid is equivocal. Eight craniopharyngiomas and ten epidermoids (including three dermoids) as well as nine rat (Wistar) abdominal skins that acted...
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Article
Distribution of cellular carbohydrate moieties in human dysontogenetic brain tumors, especially in craniopharyngioma and epidermoid/dermoid
Cellular carbohydrate moieties of 65 human dysontogenetic brain tumors (craniopharyngioma, epidermoid/dermoid, Rathke cleft cyst, germinoma and non-germinomatous germ-cell tumors) and 60 common brain tumors (g...
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Article
Intracranial cavernous angioma in the 1st year of life and a review of the literature
Three cases of symptomatic cavernous angioma occurring in the 1st year of life are presented. All three patients were treated with radical extirpation. Postoperatively, two of them improved, but the third died...
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Article
Rapid detection of proliferating potential in human brain tumors by nucleolar organizer region staining on squash preparations
Rapid detection of the proliferating potential of 37 human brain tumors was attempted using squash preparations stained by a silver colloid technique for argyrophilic protein associated with nucleolar organize...
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Article
Assessment of proliferative potential in gliomatosis cerebri
The proliferative potential of neoplastic cells in two cases of gliomatosis cerebri was investigated by a combined staining technique, a one-step silver colloid method for nucleolar organizer region-associated...
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Chapter
Glutathione S-Transferase Placental Form in Human and Rat Gliomas and Its Possible Role in Drug Resistance
Glutathione S-transferases (GSTs) are an important family of the detoxifying enzymes catalyzing the conjugation of glutathione to a wide variety of hydrophobic electrophilic substances [1]. GSTs have various i...
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Chapter
Rapid Assessment of Malignancy in Human Brain Tumors on Squash Preparations Using Nucleolar Organizer Region Staining
The intraoperative histologic diagnosis on conventional rapid frozen sections is very helpful in deciding the area to be resected during the operation of a brain tumor. However, the inadequately conserved cons...
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Article
Surgical indications for infantile subdural effusion
Thirty-four cases of infantile subdural effusion (ISE) were reviewed in relation to surgical treatment and its prognosis during an average of 4 years of extended follow-up. The surgical indications were determ...
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Chapter
Clinical Analysis with 51 Cases of Meningocele and Meningomyelocele, with Special Reference to Hydrocephalus
Fifty-one cases with meningocele (MC), meningomyelocele (MMC), and encephalocele (EC) were analysed in association with the occurrence of hydrocephalus. The incidence of hydrocephalus for all cases was 56.9% o...
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Chapter
Central Nervous Cryptococcosis Giving Rise to Ascites after Ventriculo-peritoneal Shunting: Case report
The ascites retention as a complication after V-P shunt is very rare. In this paper, a case of central nervous cryptococcosis giving rise to ascites after a V-P shunt is presented. A 45-year-old female was ref...
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Chapter
Surgical Treatment for Infantile Subdural Fluid Collections
Sixteen cases with infantile subdural fluid collections (SFC), which had no history of antecedent head injury, birth trauma, or intracranial infection, with onset symptoms of macrocrania (8 cases) and general ...