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  1. Article

    Open Access

    The non-antibiotic macrolide EM900 attenuates HDM and poly(I:C)-induced airway inflammation with inhibition of macrophages in a mouse model

    Macrolides have been reported to reduce the exacerbation of severe asthma. The aim of this study was to clarify the effects and mechanisms of EM900, a non-antibiotic macrolide, on allergic airway inflammation.

    Hironori Sadamatsu, Koichiro Takahashi, Hiroki Tashiro, Go Kato… in Inflammation Research (2020)

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  2. Article

    Open Access

    Saturated Fatty Acid Increases Lung Macrophages and Augments House Dust Mite-Induced Airway Inflammation in Mice Fed with High-Fat Diet

    Obesity is one of the phenotypes of severe asthma, which is considered to be a heterogeneous syndrome; however, its interaction with airway inflammation is not fully understood. The aim of this study was to cl...

    Hiroki Tashiro, Koichiro Takahashi, Hironori Sadamatsu, Go Kato… in Inflammation (2017)

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  3. Article

    Open Access

    β2 adrenergic agonist attenuates house dust mite-induced allergic airway inflammation through dendritic cells

    Long-acting β2 adrenergic agonists (LABAs) are commonly used combined with inhaled corticosteroids (ICS) to treat asthmatic patients. Previous reports suggest that LABAs have an anti-inflammatory effect in bro...

    Go Kato, Koichiro Takahashi, Hiroki Tashiro, Keigo Kurata… in BMC Immunology (2014)

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