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  1. Article

    Open Access

    A High-Fat Diet Increases Activation of the Glucagon-Like Peptide-1-Producing Neurons in the Nucleus Tractus Solitarii: an Effect that is Partially Reversed by Drugs Normalizing Glycemia

    Glucagon-like peptide-1 (GLP-1) is a peripheral incretin and centrally active peptide produced in the intestine and nucleus tractus solitarii (NTS), respectively. GLP-1 not only regulates metabolism but also i...

    Grazyna Lietzau, Stelia Ntika, Hiranya Pintana… in Cellular and Molecular Neurobiology (2022)

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  2. Article

    Open Access

    The Stroke-Induced Increase of Somatostatin-Expressing Neurons is Inhibited by Diabetes: A Potential Mechanism at the Basis of Impaired Stroke Recovery

    Type 2 diabetes (T2D) hampers recovery after stroke, but the underling mechanisms are mostly unknown. In a recently published study (Pintana et al. in Clin Sci (Lond) 133(13):1367–1386, 2019), we showed that i...

    Fausto Chiazza, Hiranya Pintana, Grazyna Lietzau… in Cellular and Molecular Neurobiology (2021)

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  3. Article

    Open Access

    Type 2 diabetes impairs odour detection, olfactory memory and olfactory neuroplasticity; effects partly reversed by the DPP-4 inhibitor Linagliptin

    Recent data suggest that olfactory deficits could represent an early marker and a pathogenic mechanism at the basis of cognitive decline in type 2 diabetes (T2D). However, research is needed to further charact...

    Grazyna Lietzau, William Davidsson… in Acta Neuropathologica Communications (2018)

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