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  1. No Access

    Article

    Autophagic activity in thymus and liver during aging

    Impaired or deficient autophagy is believed to cause or contribute to aging, as well as several age-related pathologies. Thymic epithelial cells had a high constitutive level of autophagy. The autophagic proce...

    Mohammad Nizam Uddin, Naomi Nishio, Sachiko Ito, Haruhiko Suzuki, Ken-ichi Isobe in AGE (2012)

  2. No Access

    Article

    Linkage between melanocytic tumor development and early burst of Ret protein expression for tolerance induction in metallothionein-I/ret transgenic mouse lines

    We examined the basis of the all or none difference in inducing melanocytic tumor development among three transgenic mouse lines (304, 192 and 242) to which the same promoter-enhancer (metallothionein-I) and o...

    Masashi Kato, Wei Liu, Anwarul A Akhand, Yan Dai, Masaharu Ohbayashi… in Oncogene (1999)

  3. No Access

    Article

    Transgenic mouse model for skin malignant melanoma

    We report here on a novel metallothionein-I (MT)/ret transgenic mouse line in which skin melanosis, benign melanocytic tumor and malignant melanoma metastasizing to distant organs develop stepwise. The process of...

    Masashi Kato, Masahide Takahashi, Anwarul A Akhand, Wei Liu, Yan Dai… in Oncogene (1998)