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  1. Article

    Open Access

    Tracking the origins and drivers of subclonal metastatic expansion in prostate cancer

    Tumour heterogeneity in primary prostate cancer is a well-established phenomenon. However, how the subclonal diversity of tumours changes during metastasis and progression to lethality is poorly understood. He...

    Matthew K.H. Hong, Geoff Macintyre, David C. Wedge, Peter Van Loo… in Nature Communications (2015)

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  2. No Access

    Article

    Reprogramming roadmap reveals route to human induced trophoblast stem cells

    The reprogramming of human somatic cells to primed or naive induced pluripotent stem cells recapitulates the stages of early embryonic development1–6. The molecular mechanism that underpins these reprogramming pr...

    **aodong Liu, John F. Ouyang, Fernando J. Rossello, Jia ** Tan… in Nature (2020)

  3. Article

    Open Access

    Thousands of Qatari genomes inform human migration history and improve imputation of Arab haplotypes

    Arab populations are largely understudied, notably their genetic structure and history. Here we present an in-depth analysis of 6,218 whole genomes from Qatar, revealing extensive diversity as well as genetic ...

    Rozaimi Mohamad Razali, Juan Rodriguez-Flores… in Nature Communications (2021)

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