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Article
Clostridium difficile, the Difficult “Kloster” Fuelled by Antibiotics
Clostridium difficile is normally present in low numbers in a healthy adult gastro-intestinal tract (GIT). Drastic changes in the microbial population, e.g., dysbiosis caused by extensive treatment with antibioti...
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Article
Open AccessLactobacillus delivery of bioactive interleukin-22
Interleukin-22 (IL-22) plays a prominent role in epithelial regeneration and dampening of chronic inflammatory responses by protecting intestinal stem cells from immune-mediated tissue damage. IL-22 has a cons...
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Article
Screening and Evaluation of Human Intestinal Lactobacilli for the Development of Novel Gastrointestinal Probiotics
The aim of this study was to screen intestinal lactobacilli strains for their advantageous properties to select those that could be used for the development of novel gastrointestinal probiotics. Ninety-three i...
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Article
Open AccessEffective prophylaxis against rotavirus diarrhea using a combination of Lactobacillus rhamnosus GG and antibodies
Rotavirus is a worldwide cause of infectious infantile diarrhea that claims over 600,000 lives annually. Recently, two new vaccine candidates have been developed but their efficacy in develo** countries, sti...
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Article
Therapeutic effect of llama derived VHH fragments against Streptococcus mutans on the development of dental caries
Streptococcus mutans is the main cause of dental caries. We evaluated the therapeutic effect of variable regions of a llama heavy chain antibody fragments directed against S. mutans named S36-VHH (S for Streptoco...