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  1. No Access

    Article

    Alpha-synuclein in peripheral body fluid as a biomarker for Parkinson’s disease

    Whether alpha-synuclein in peripheral body fluids can be used for the diagnosis of Parkinson’s disease (PD) remains in controversy. This study evaluates diagnostic potential of alpha-synuclein for PD in variou...

    Hao Shu, Pengcheng Zhang, Lihua Gu in Acta Neurologica Belgica (2024)

  2. No Access

    Article

    Soluble TREM2 in body fluid in Alzheimer’s disease and Parkinson’s disease

    Previous studies showed conflicting results regarding soluble triggering receptor expressed on myeloid cells 2 (sTREM2) level alteration in body fluid in Alzheimer’s disease (AD) and Parkinson’s disease (PD).

    Lihua Gu, Hao Shu, Yanjuan Wang in Neurological Sciences (2023)

  3. No Access

    Article

    Functional brain changes in Parkinson’s disease: a whole brain ALE study

    Resting-state functional magnetic resonance imaging (rs-fMRI) was widely used as an effective tool in the diagnosis of neurodegenerative diseases. However, prior rs-fMRI studies reported inconsistent results f...

    Lihua Gu, Hao Shu, Hui Xu, Yanjuan Wang in Neurological Sciences (2022)

  4. No Access

    Article

    Intrinsic connectivity identifies the sensory-motor network as a main cross-network between remitted late-life depression- and amnestic mild cognitive impairment-targeted networks

    Remitted late-life depression (rLLD) and amnestic mild cognitive impairment (aMCI) are both associated with a high risk of develo** Alzheimer’s disease (AD). Neurodegeneration is considered to spread within ...

    Jiu Chen, Hao Shu, Zan Wang, Yafeng Zhan, Duan Liu, Yong Liu… in Brain Imaging and Behavior (2020)

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    Article

    Distinct neural correlates of episodic memory among apolipoprotein E alleles in cognitively normal elderly

    The apolipoprotein E (APOE) ε4 and ε2 alleles are acknowledged genetic factors modulating Alzheimer’s disease (AD) risk and episodic memory (EM) deterioration in an opposite manner. Mounting neuroimaging studi...

    Hao Shu, Yongmei Shi, Gang Chen, Zan Wang, Duan Liu… in Brain Imaging and Behavior (2019)

  6. No Access

    Article

    The apolipoprotein E gene affects the three-year trajectories of compensatory neural processes in the left-lateralized hippocampal network

    Previous cross-sectional studies that investigated the effects of apolipoprotein E (ApoE) ε4 status on hippocampal networks have shown inconsistent results. Aging is a well-known risk factor for Alzheimer’s di...

    Qing Ye, Fan Su, Hao Shu, Liang Gong, Chunming **e… in Brain Imaging and Behavior (2017)