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Article
Chemical short-range disorder in lithium oxide cathodes
Ordered layered structures serve as essential components in lithium (Li)-ion cathodes1–3. However, on charging, the inherently delicate Li-deficient frameworks become vulnerable to lattice strain and structural a...
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Article
Open AccessSelf-similarity study based on the particle sizes of coal-series diatomite
Coal-series diatomite (CSD) is widely distributed in China and has poor functional and structural properties and exhibits limited utilization of high value-added materials, resulting in a serious waste of reso...
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Article
Open AccessResearch on the "shape-performance-control" integrated digital twin system for boom-type roadheaders
The boom-type roadheader plays a crucial role in coal mining. However, conducting the real-time monitoring of the mechanical performance and comprehensive adaptive cutting in the dynamic cutting process are ch...
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Article
Open AccessDesigning lithium halide solid electrolytes
All-solid-state lithium batteries have attracted widespread attention for next-generation energy storage, potentially providing enhanced safety and cycling stability. The performance of such batteries relies o...
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Article
Open AccessElectrophotocatalytic hydrogenation of imines and reductive functionalization of aryl halides
The open-shell catalytically active species, like radical cations or radical anions, generated by one-electron transfer of precatalysts are widely used in energy-consuming redox reactions, but their excited-st...
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Article
Open AccessResearch on the comparison of impact resistance characteristics between energy absorption and conventional hydraulic columns in fluid–solid coupling
Rock burst disaster affects underground mining safety. The energy-absorbing hydraulic support for preventing tunnel impact has been implemented in rock burst mines. In order to compare the impact resistance ch...
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Article
Open AccessSequence-based drug design as a concept in computational drug design
Drug development based on target proteins has been a successful approach in recent decades. However, the conventional structure-based drug design (SBDD) pipeline is a complex, human-engineered process with mul...
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Article
Open AccessPrognostic implications of N6-methyladenosine RNA regulators in breast cancer
The significance of N6-methyladenosine (m6A) RNA modifications in the progression of breast cancer (BC) has been recognised. However, their potential role and mechanism of action in the tumour microenvironment (T...
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Article
Open AccessThe maintenance of microbial community in human fecal samples by a cost effective preservation buffer
In the burgeoning microbiome field, powerful sequencing approaches and accompanied bioanalytical methods have made tremendous contributions to the discoveries of breakthroughs, which favor to unravel the intim...
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Article
Author Correction: AIM2 in regulatory T cells restrains autoimmune diseases
A Correction to this paper has been published: https://doi.org/10.1038/s41586-021-03490-7.
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Article
AIM2 in regulatory T cells restrains autoimmune diseases
The inflammasome initiates innate defence and inflammatory responses by activating caspase-1 and pyroptotic cell death in myeloid cells1,2. It consists of an innate immune receptor/sensor, pro-caspase-1, and a co...
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Article
Open AccessComparison of cord blood hematological parameters among normal, α-thalassemia, and β-thalassemia fetuses between 17 and 38 weeks of gestation
The aim of this study was to retrospectively compare hematological parameters among normal, α-, and β-thalassemia fetuses between 17 and 38 weeks of gestation. Pregnant women at risk of having fetuses with tha...
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Article
Open AccessXenon binding by a tight yet adaptive chiral soft capsule
Xenon binding has attracted interest due to the potential for xenon separation and emerging applications in magnetic resonance imaging. Compared to their covalent counterparts, assembled hosts that are able to...
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Article
Open AccessHistological assessment of optogenetic tools to study fronto-visual and fronto-parietal cortical networks in the rhesus macaque
Optogenetics offers unprecedented possibilities to investigate cortical networks. Yet, the number of successful optogenetic applications in non-human primates is still low, and the consequences of opsin expres...
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Article
Open AccessCathepsin S activation contributes to elevated CX3CL1 (fractalkine) levels in tears of a Sjögren’s syndrome murine model
Autoimmune dacryoadenitis and altered lacrimal gland (LG) secretion are features of Sjögren’s syndrome (SS). Activity of cathepsin S (CTSS), a cysteine protease, is significantly and specifically increased in ...
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Article
Open AccessMetabolomics Deciphered Metabolic Reprogramming Required for Biofilm Formation
Biofilm formation plays a key role in many bacteria causing infections, which mostly accounts for high-frequency infectious recurrence and antibiotics resistance. In this study, we sought to compare modified m...
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Article
Open AccessFabellar prevalence, degeneration and association with knee osteoarthritis in the Chinese population
The fabella is a sesamoid bone of the knee that can degenerate in some patients with osteoarthritis. The purpose of this study was to examine the prevalence and degeneration grades of fabellae in the Chinese p...
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Article
Open AccessInhibition of Cathepsin S Reduces Lacrimal Gland Inflammation and Increases Tear Flow in a Mouse Model of Sjögren’s Syndrome
Cathepsin S (CTSS) is highly increased in Sjögren’s syndrome (SS) patients tears and in tears and lacrimal glands (LG) of male non-obese diabetic (NOD) mice, a murine model of SS. To explore CTSS’s utility as ...
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Article
Open AccessSlab morphology and deformation beneath Izu-Bonin
Seismic tomography provides unique constraints on the morphology, the deformation, and (indirectly) the rheology of subducting slabs. We use teleseismic double-difference P-wave tomography to image with unprec...
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Article
Open AccessLaser guided ionic wind
We report on a method to experimentally generate ionic wind by coupling an external large electric field with an intense femtosecond laser induced air plasma channel. The measured ionic wind velocity could be ...