6 Result(s)
within
Hao Chi
Life Sciences
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Article
Open AccessSARS-CoV-2 envelope protein causes acute respiratory distress syndrome (ARDS)-like pathological damages and constitutes an antiviral target
Cytokine storm and multi-organ failure are the main causes of SARS-CoV-2-related death. However, the origin of excessive damages caused by SARS-CoV-2 remains largely unknown. Here we show that the SARS-CoV-2 e...
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Article
Comprehensive identification of peptides in tandem mass spectra using an efficient open search engine
Peptide identification in proteomics data is improved using an efficient open search engine.
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Article
Open AccessAccelerating the scoring module of mass spectrometry-based peptide identification using GPUs
Tandem mass spectrometry-based database searching is currently the main method for protein identification in shotgun proteomics. The explosive growth of protein and peptide databases, which is a result of geno...
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Article
Identification of cross-linked peptides from complex samples
pLink, software for data analysis of cross-linked proteins coupled with mass spectrometry, estimates false discovery rate and enables analysis of protein complexes without extensive purification.
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Article
Open AccessSpeeding up tandem mass spectrometry-based database searching by longest common prefix
Tandem mass spectrometry-based database searching has become an important technology for peptide and protein identification. One of the key challenges in database searching is the remarkable increase in comput...
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Article
Open AccessEfficient discovery of abundant post-translational modifications and spectral pairs using peptide mass and retention time differences
Peptide identification via tandem mass spectrometry is the basic task of current proteomics research. Due to the complexity of mass spectra, the majority of mass spectra cannot be interpreted at present. The e...
