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Novel rAAV vector mediated intrathecal HGF delivery has an impact on neuroimmune modulation in the ALS motor cortex with TDP-43 pathology

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  1. Article

    Open Access

    P2Y12-dependent activation of hematopoietic stem and progenitor cells promotes emergency hematopoiesis after myocardial infarction

    Emergency hematopoiesis is the driving force of the inflammatory response to myocardial infarction (MI). Increased proliferation of hematopoietic stem and progenitor cells (LSK) after MI enhances cell producti...

    Hana Seung, Jan Wrobel, Carolin Wadle, Timon Bühler in Basic Research in Cardiology (2022)

  2. Article

    Open Access

    Gene-environment interaction counterbalances social impairment in mouse models of autism

    Autism spectrum disorder (ASD) is a neurodevelopmental disorder characterized by social communication deficits and repetitive/restricted behaviors. Although gene-environment interactions may explain the hetero...

    Ji-Woon Kim, Kwanghoon Park, Ri ** Kang, Edson Luck Gonzales in Scientific Reports (2019)

  3. Article

    Open Access

    Social support rescues acute stress-induced cognitive impairments by modulating ERK1/2 phosphorylation in adolescent mice

    Social support can relieve stress-induced behavioural outcomes, although its underlying molecular mechanisms are not fully understood. Here, we evaluated whether social interactions can prevent the restraint s...

    Ji-Woon Kim, Mee Jung Ko, Edson Luck Gonzales, Ri ** Kang in Scientific Reports (2018)

  4. Article

    Open Access

    Gastrointestinal Tract Abnormalities Induced by Prenatal Valproic Acid Exposure in Rat Offspring

    In-utero exposure to valproic acid (VPA) has been known as a potent inducer of autism spectrum disorder (ASD), not only in humans, but also in animals. In addition to the defects in communication and social inter...

    Ji-Woon Kim, Chang Soon Choi, Ki Chan Kim, ** Hee Park in Toxicological Research (2013)