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  1. Article

    Open Access

    Methylomics and cancer: the current state of methylation profiling and marker development for clinical care

    Epigenetic modifications have long been recognized as an essential level in transcriptional regulation linking behavior and environmental conditions or stimuli with biological processes and disease development...

    Chengyin Liu, Han Tang, Nana Hu, Tianbao Li in Cancer Cell International (2023)

  2. Article

    Open Access

    Publisher Correction: Neoadjuvant adebrelimab in locally advanced resectable esophageal squamous cell carcinoma: a phase 1b trial

    Jun Yin, **gnan Yuan, Yun** Li, Yong Fang, Ruoxi Wang, Heng Jiao in Nature Medicine (2023)

  3. Article

    Open Access

    Neoadjuvant adebrelimab in locally advanced resectable esophageal squamous cell carcinoma: a phase 1b trial

    Overall survival (OS) benefits of neoadjuvant immunotherapy remain elusive in locally advanced esophageal squamous cell carcinomas (ESCC). Here, we reported the results of a phase 1b trial of neoadjuvant PD-L1...

    Jun Yin, **gnan Yuan, Yun** Li, Yong Fang, Ruoxi Wang, Heng Jiao in Nature Medicine (2023)

  4. Article

    Open Access

    Adverse reactions of targeted therapy in cancer patients: a retrospective study of hospital medical data in China

    The adverse reactions (ADRs) of targeted therapy were closely associated with treatment response, clinical outcome, quality of life (QoL) of patients with cancer. However, few studies presented the correlation...

    Ruofei Du, **n Wang, Lixia Ma, Leon M. Larcher, Han Tang, Huiyue Zhou in BMC Cancer (2021)

  5. Article

    Open Access

    CMISG1701: a multicenter prospective randomized phase III clinical trial comparing neoadjuvant chemoradiotherapy to neoadjuvant chemotherapy followed by minimally invasive esophagectomy in patients with locally advanced resectable esophageal squamous cell carcinoma (cT3-4aN0-1M0) (NCT03001596)

    Neoadjuvant chemoradiation is not recommended as an approach for treatment of esophageal squamous cell carcinoma due to its significant postoperative mortality. However, it is assumed the combination of neoadj...

    Han Tang, Lijie Tan, Yaxing Shen, Hao Wang, Miao Lin, Mingxiang Feng in BMC Cancer (2017)