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Open AccessPolygenic risk score for tumor aggressiveness and early-onset prostate cancer in Asians
We attempted to assess the performance of an ethnic-specific polygenic risk score (PRS) designed from a Korean population to predict aggressive prostate cancer (PCa) and early-onset (age < 60). A PRS score com...
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Article
Open AccessHeavy metal removal using an advanced removal method to obtain recyclable paper incineration ash
Various agents, including ethylenediaminetetraacetic acid, oxalic acid, citric acid, and HCl, were applied to remove heavy metals from raw paper incineration ash and render the ash recyclable. Among these prep...
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Article
Open AccessKoVariome: Korean National Standard Reference Variome database of whole genomes with comprehensive SNV, indel, CNV, and SV analyses
High-coverage whole-genome sequencing data of a single ethnicity can provide a useful catalogue of population-specific genetic variations, and provides a critical resource that can be used to more accurately i...
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Open AccessCorrection: Corrigendum: An ethnically relevant consensus Korean reference genome is a step towards personal reference genomes
Nature Communications 7: Article number: 13637 (2016): Published 24 November 2016; Updated 9 October 2017. The original version of this Article contained an error in the email address of the corresponding auth...
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Open AccessAn ethnically relevant consensus Korean reference genome is a step towards personal reference genomes
Human genomes are routinely compared against a universal reference. However, this strategy could miss population-specific and personal genomic variations, which may be detected more efficiently using an ethnic...
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Open AccessWhole genome comparison of donor and cloned dogs
Cloning is a process that produces genetically identical organisms. However, the genomic degree of genetic resemblance in clones needs to be determined. In this report, the genomes of a cloned dog and its dono...
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Open AccessThe tiger genome and comparative analysis with lion and snow leopard genomes
Tigers and their close relatives (Panthera) are some of the world’s most endangered species. Here we report the de novo assembly of an Amur tiger whole-genome sequence as well as the genomic sequences of a white ...