233 Result(s)
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Open AccessObservation of stacking engineered magnetic phase transitions within moiré supercells of twisted van der Waals magnets
Recent demonstrations of moiré magnetism, featuring exotic phases with noncollinear spin order in the twisted van der Waals (vdW) magnet chromium triiodide CrI3, have highlighted the potential of twist engineerin...
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Open AccessIdentification of hub genes associated with diabetic cardiomyopathy using integrated bioinformatics analysis
Diabetic cardiomyopathy (DCM) is a common cardiovascular complication of diabetes, which may threaten the quality of life and shorten life expectancy in the diabetic population. However, the molecular mechanis...
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Open AccessGlobal variability in atmospheric new particle formation mechanisms
A key challenge in aerosol pollution studies and climate change assessment is to understand how atmospheric aerosol particles are initially formed1,2. Although new particle formation (NPF) mechanisms have been de...
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Open AccessA microscopic mechanism study of the effect of binary surfactants on the flotation of Wiser bituminous coal
Investigating surfactant effects on the floatability of Wiser bituminous coal holds significant importance in improving coal cleanliness and utilization value. Using density functional theory and molecular dyn...
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Open AccessEmergence of decadal linkage between Western Australian coast and Western–central tropical Pacific
The impact of interbasin linkage on the weather/climate and ecosystems is significantly broader and profounder than that of only appearing in an individual basin. Here, we reveal that a decadal linkage of sea ...
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Open AccessGenome-wide identification and analysis of epithelial-mesenchymal transition-related RNA-binding proteins and alternative splicing in a human breast cancer cell line
Exploring the mechanism of breast cancer metastasis and searching for new drug therapeutic targets are still the focuses of current research. RNA-binding proteins (RBPs) may affect breast cancer metastasis by ...
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Open AccessDrug screening on digital microfluidics for cancer precision medicine
Drug screening based on in-vitro primary tumor cell culture has demonstrated potential in personalized cancer diagnosis. However, the limited number of tumor cells, especially from patients with early stage ca...
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Open AccessMendelian randomization analysis reveals causal associations of serum metabolites with sepsis and 28-day mortality
Metabolic disorder has been found to be an important factor in the pathogenesis and progression of sepsis. However, the causation of such an association between serum metabolites and sepsis has not been establ...
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Open AccessDamage prediction and improvement method based on cutting mode of circular empty hole
Based on the theory of empty hole effect of cutting blasting, the Hopkinson effect and Saint–Venant principle are integrated to establish a two-dimensional calculation model of dynamic stress evolution of the ...
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Open AccessBaicalin enhances the chemotherapy sensitivity of oxaliplatin-resistant gastric cancer cells by activating p53-mediated ferroptosis
Gastric cancer is one of the most common malignant tumors, and chemotherapy is the main treatment for advanced gastric cancer. However, chemotherapy resistance leads to treatment failure and poor prognosis in ...
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Open AccessEtiologic evaluation and pregnancy outcomes of fetal growth restriction (FGR) associated with structural malformations
This study aimed to evaluate the etiology and pregnancy outcomes of fetuses underwent invasive prenatal diagnosis for fetal growth restriction (FGR) accompanied by structural malformations. Data from 130 pregn...
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Open AccessCXCL5 activates CXCR2 in nociceptive sensory neurons to drive joint pain and inflammation in experimental gouty arthritis
Gouty arthritis evokes joint pain and inflammation. Mechanisms driving gout pain and inflammation remain incompletely understood. Here we show that CXCL5 activates CXCR2 expressed on nociceptive sensory neuron...
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Open AccessQuantum phase synchronization via exciton-vibrational energy dissipation sustains long-lived coherence in photosynthetic antennas
The lifetime of electronic coherences found in photosynthetic antennas is known to be too short to match the energy transfer time, rendering the coherent energy transfer mechanism inactive. Exciton-vibrational...
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Open AccessA dual diffusion model enables 3D molecule generation and lead optimization based on target pockets
Structure-based generative chemistry is essential in computer-aided drug discovery by exploring a vast chemical space to design ligands with high binding affinity for targets. However, traditional in silico me...
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Open AccessFlexible temperature-pressure dual sensor based on 3D spiral thermoelectric Bi2Te3 films
Dual-parameter pressure-temperature sensors are widely employed in personal health monitoring and robots to detect external signals. Herein, we develop a flexible composite dual-parameter pressure-temperature ...
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Open AccessThe role of interdecadal climate oscillations in driving Arctic atmospheric river trends
Atmospheric rivers (ARs), intrusions of warm and moist air, can effectively drive weather extremes over the Arctic and trigger subsequent impact on sea ice and climate. What controls the observed multi-decadal...
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Open AccessEfficient direct repairing of lithium- and manganese-rich cathodes by concentrated solar radiation
Lithium- and manganese-rich layered oxide cathode materials have attracted extensive interest because of their high energy density. However, the rapid capacity fading and serve voltage decay over cycling make ...
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Open AccessDeep clustering using 3D attention convolutional autoencoder for hyperspectral image analysis
Deep clustering has been widely applicated in various fields, including natural image and language processing. However, when it is applied to hyperspectral image (HSI) processing, it encounters challenges due ...
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Open AccessA dual-crosslinking electroactive hydrogel based on gelatin methacrylate and dibenzaldehyde-terminated telechelic polyethylene glycol for 3D bio-printing
Gelatin was widely used as scaffold materials in 3D bio-printing due to its excellent bioactivity and availability and especially that their arginine–glycine–aspartic acid (RGD) sequences could efficiently pro...
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Open AccessRecovery of 1887 metagenome-assembled genomes from the South China Sea
The South China Sea (SCS) is a marginal sea characterized by strong land-sea biogeochemical interactions. SCS has a distinctive landscape with a multitude of seamounts in its basin. Seamounts create “seamount ...
